ArticleInvestigative ophthalmology & visual science2024
Multifaceted Interactions of Stereoacuity, Inter-Ocular Suppression, and Fixation Eye Movement Abnormalities in Amblyopia and Strabismus.
Article in Investigative ophthalmology & visual science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 12 citations in OpenAlex.
- Amblyopia Severity Predicts Fixation Dysfunction Independent of Nystagmus and Foveation Disruption in Fusion Maldevelopment Nystagmus.Investigative ophthalmology & visual science · 2026Article
- Psychometric Performance of Children With Amblyopia During a Tablet-Based Adaptive Visual Acuity Assessment.Investigative ophthalmology & visual science · 2026Article
- Visually Guided Saccades in Amblyopia and Strabismus: The Roles of Sensory Deficits and Nystagmus.Investigative ophthalmology & visual science · 2026Article
- Differential Fixation and Eye Alignment Patterns in Strabismus with and Without Amblyopia Across Viewing Conditions.Journal of eye movement research · 2026Article
- "Look Versus See": Does Varying Fellow Eye Contrast Affect Perception of the Amblyopic Eye?Investigative ophthalmology & visual science · 2026Article
- Effect of active vision therapy on contrast sensitivity in bilateral amblyopia.International journal of ophthalmology · 2026Article
- Exploration of visual perception metrics as indicators for myopia screening.Lasers in medical science · 2025Article
- Dichoptic Visual Search at Varied Fellow Eye Contrasts and Visual Function Deficits in Amblyopia.Investigative ophthalmology & visual science · 2025Article
- Psychophysical assessment of face perception deficits in adults with amblyopia through top-down and bottom-up visual processing pathways.Frontiers in neuroscience · 2025Article
- Evaluating Eye Tracking During Dichoptic Video Viewing With Varied Fellow Eye Contrasts in Amblyopia.Investigative ophthalmology & visual science · 2024Article
- Assessing inter-ocular fixational eye movements throughout the lifespan.Experimental brain research · 2024Article
- A Multihead Attention Deep Learning Algorithm to Detect Amblyopia Using Fixation Eye Movements.Ophthalmology scienceArticle
- Leveraging neural plasticity for the treatment of amblyopia.Survey of ophthalmologyReview
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Purpose: Amblyopic and strabismus subjects experience inter-ocular suppression, impaired stereoacuity, and increased fixation instability. The purpose of the study was to investigate factors affecting suppression and stereoacuity and examine their relationship to fixation eye movement (FEM) abnormalities. Methods: We recruited 14 controls and 46 amblyopic subjects (anisometropic = 18, strabismic = 14, and mixed = 14) and 11 subjects with strabismus without amblyopia. We utilized the dichoptic motion coherence test to quantify suppression, and stereoacuity was assessed using the Titmus Fly test. We recorded FEMs using high-resolution video-oculography and classified subjects that did not have nystagmus (n = 27) versus those with nystagmus (n = 32; fusion maldevelopment nystagmus [FMN], n = 10) and nystagmus that did not meet the criteria of FMN (n = 20). We also recorded FEMs under dichoptic viewing (DcV) at varied fellow eye (FE) contrasts and computed the amplitude and velocity of the fast and slow FEMs and vergence instability. Results: Inter-ocular suppression and stereoacuity deficits were closely correlated with an amblyopic eye (AE), visual acuity, and strabismus angle. Subjects with nystagmus displayed more pronounced stereoacuity deficits than those without nystagmus. Strabismic subjects with and without amblyopia, who demonstrated a fixation switch at 100% FE contrast, had lower inter-ocular suppression than subjects lacking a fixation switch under DcV. Amplitude of fast FEMs and velocity of slow FEMs, and vergence instability were increased as the FE contrast was lowered in both amblyopic and strabismic subjects. Conclusions: The current study highlights the intricate relationships between AE visual acuity, eye deviation, and FEM abnormalities on suppression and stereoacuity deficits and underscores the need to evaluate FEM abnormalities while assessing dichoptic treatment outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.