Evidence map›Paper›PMID 38470195›Full record

ArticleAntimicrobial agents and chemotherapy2024

Murepavadin promotes the killing efficacies of aminoglycoside antibiotics against

Xiaoya Wei, Jiacong Gao, Dandan Zhou, Congjuan Xu, Ping Chen, Shuiping Chen, Yanhong Zhang, Xuehua Liu, Guanxian Li, Guangbo Zhu and 10 more

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. TheFrontiers in cellular and infection microbiology · 2026
    Article
  3. Review
  4. Anaerobiosis and Mutations Can Reduce Susceptibility ofPathogens (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 2 countries.

Xiaoya WeiState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China.ORCID 0000-0001-5681-0764
Jiacong GaoState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China.
Dandan ZhouState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China.
Congjuan XuState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China.
Ping ChenState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China.
Shuiping ChenDepartment of Laboratory Medicine, 5th Medical Center of PLA General Hospital, Beijing, China.
Yanhong ZhangNankai University Affiliated Hospital (Tianjin Forth Hospital), Tianjin, China.
Xuehua LiuTianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China.
Guanxian LiTianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China.
Guangbo ZhuTianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China.
Huimin LiuTianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China.
Jinjin LiTianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China.
Bin GengTianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China.
Linlin GaoTianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China.
Zhihui ChengState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China.
Iain L LamontDepartment of Biochemistry, University of Otago, Dunedin, New Zealand.ORCID 0000-0002-7601-6354
Daniel PletzerDepartment of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.ORCID 0000-0001-5750-7505
Yongxin JinState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China.ORCID 0000-0002-1449-6735
Shouguang JinState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China.
Weihui WuState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China.ORCID 0000-0002-9017-0091
Nankai University · CNUniversity of Otago · NZChinese PLA General Hospital · CN

Funding

MOST | National Key Research and Development Program of China (NKPs) 2021YFE0101700MOST | National Natural Science Foundation of China (NSFC) 32170177MOST | National Natural Science Foundation of China (NSFC) 32170199Nankai University Tianjin Applied and Fundamental Reasearch Project 22JCZDJC0041
6 · The paper itself

Abstract

Murepavadin is a peptidomimetic that specifically targets the lipopolysaccharide transport protein LptD of

Indexed as

AmikacinPeptides, CyclicPseudomonas InfectionsAminoglycosidesAnimalsAnti-Bacterial AgentsMembrane PotentialsMiceMicrobial Sensitivity TestsPseudomonas aeruginosaTobramycinAmikacinAminoglycosidesAnti-Bacterial AgentsmurepavadinPeptides, CyclicTobramycinaminoglycoside antibioticsmurepavadinPseudomonas aeruginosa

Identifiers

PMID38470195
PMCPMC10989017
OpenAlexW4392893140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.