Evidence map›Paper›PMID 38470142›Full record

ArticlemSystems2024

Diversity and distribution of biosynthetic gene clusters in agricultural soil microbiomes.

Zhiguo Zhang, Lu Zhang, Lihan Zhang, Haiyan Chu, Jizhong Zhou, Feng Ju

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 26 citations in OpenAlex.

  1. Exploring the antifungal activity of the wheat microbiome.Biochemical Society transactions · 2026
    Review
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  5. Impacts of different ozone treatments on the growth and soil bacterial community of Pinellia ternata.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Zhiguo ZhangCollege of Environmental and Resource Sciences, Zhejiang University, Hangzhou, Zhejiang, China.ORCID 0000-0002-3265-4936
Lu ZhangKey Laboratory of Coastal Environment and Resources Research of Zhejiang Province, School of Engineering, Westlake University, Hangzhou, Zhejiang, China.
Lihan ZhangInstitute of Natural Sciences, Westlake Institute for Advanced Study, Hangzhou, Zhejiang, China.ORCID 0000-0003-4364-6242
Haiyan ChuState Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing, China.ORCID 0000-0001-9004-8750
Jizhong ZhouDepartment of Microbiology and Plant Biology, Institute for Environmental Genomics, University of Oklahoma, Norman, Oklahoma, USA.
Feng JuKey Laboratory of Coastal Environment and Resources Research of Zhejiang Province, School of Engineering, Westlake University, Hangzhou, Zhejiang, China.ORCID 0000-0003-4137-5928
Westlake University · CNChinese Academy of Sciences · CNUniversity of Oklahoma · US

Funding

National Natural Science Foundation of China (NSFC) 22241603The "Pioneer" and "Leading Goose" R&D Program of Zhejiang 2024SSYS0032Zhejiang Provincial Natural Science Foundation of China LR22D010001
6 · The paper itself

Abstract

Bacterial secondary metabolites serve as an important source of molecules for drug discovery. They also play an important function in mediating the interactions of microbial producers with their living environment and surrounding organisms. However, little is known about the genetic novelty, distribution, and community-level impacts of soil bacterial biosynthetic potential on a large geographic scale. Here, we constructed the first catalog of 11,149 biosynthetic gene clusters (BGCs) from agricultural soils across China and unearthed hidden biosynthetic potential for new natural product discovery from the not-yet-cultivated soil bacteria. Notably, we revealed soil pH as the strongest environmental driver of BGC biogeography and predicted that soil acidification and global climate change could damage the biosynthetic potential of the soil microbiome. The co-occurrence network of bacterial genomes revealed two BGC-rich species, i.e.,

Indexed as

MicrobiotaSoilBacteriaMultigene FamilyPhylogenySoil MicrobiologySoilagricultural soil microbiomebiosynthetic gene clustersdiversityMicrobial community assemblySecondary metabolite

Identifiers

PMID38470142
PMCPMC11019929
OpenAlexW4392727661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.