Evidence map›Paper›PMID 38470131›Full record

ReviewmSphere2024

Advanced genetic techniques in fungal pathogen research.

Robbi L Ross, Felipe H Santiago-Tirado

Open access · goldAbstract readReview
In one paragraph

Review in mSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Cryptococcus.Current biology : CB · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Robbi L RossDepartment of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
Felipe H Santiago-TiradoDepartment of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.ORCID 0000-0002-6453-4904
University of Notre Dame · US

Funding

Host and fungal factors important for the cryptococcal intracellular nicheR01AI177875 · NIAID · UNIVERSITY OF NOTRE DAME · PI Felipe H Santiago-Tirado · 2023 to 2026
$1.6M
The role of a pleiotropic drug resistance (PDR) transporter in the cryptococcal-host interactionsR21AI171742 · NIAID · UNIVERSITY OF NOTRE DAME · PI SANTIAGO-TIRADO, FELIPE H · 2023 to 2024
$430k
NIAID NIH HHS R01 AI177875NIAID NIH HHS R21 AI171742
6 · The paper itself

Abstract

Although fungi have been important model organisms for solving genetic, molecular, and ecological problems, recently, they are also becoming an important source of infectious disease. Despite their high medical burden, fungal pathogens are understudied, and relative to other pathogenic microbes, less is known about how their gene functions contribute to disease. This is due, in part, to a lack of powerful genetic tools to study these organisms. In turn, this has resulted in inappropriate treatments and diagnostics and poor disease management. There are a variety of reasons genetic studies were challenging in pathogenic fungi, but in recent years, most of them have been overcome or advances have been made to circumvent these barriers. In this minireview, we highlight how recent advances in genetic studies in fungal pathogens have resulted in the discovery of important biology and potential new antifungals and have created the tools to comprehensively study these important pathogens.

Indexed as

FungiMycosesAntifungal AgentsGenetic TechniquesHumansAntifungal AgentsAspergillusCandidaCryptococcusfungal geneticsfungal pathogen

Identifiers

PMID38470131
PMCPMC11036804
OpenAlexW4392703660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.