Evidence map›Paper›PMID 38470030›Full record

ArticleApplied and environmental microbiology2024

Development of a genetic system for

Colin Tittes, Jeroen Nijland, Anna M C Schoentag, Thomas Hackl, Nadia Di Cianni, Anita Marchfelder, Tessa E F Quax

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Colin TittesBiology of Archaea and Viruses, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, the Netherlands.ORCID 0000-0002-2335-6662
Jeroen NijlandBiology of Archaea and Viruses, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, the Netherlands.
Anna M C SchoentagBiology of Archaea and Viruses, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, the Netherlands.
Thomas HacklMicrobial Ecology Cluster, Groningen Institute of Evolutionary Life Sciences, University of Groningen, Groningen, the Netherlands.
Nadia Di CianniBiology II, Ulm University, Ulm, Germany.
Anita MarchfelderBiology II, Ulm University, Ulm, Germany.ORCID 0000-0002-1382-1794
Tessa E F QuaxBiology of Archaea and Viruses, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, the Netherlands.ORCID 0000-0001-5516-5871
University of Groningen · NLUniversität Ulm · DE

Funding

Deutsche Forschungsgemeinschaft (DFG)EC | European Research Council (ERC)
6 · The paper itself

Abstract

Archaeal viruses are among the most enigmatic members of the virosphere, and their diverse morphologies raise many questions about their infection mechanisms. The study of molecular mechanisms underlying virus-host interactions hinges upon robust model organisms with a system for gene expression and deletion. Currently, there are only a limited number of archaea that have associated viruses and have a well-developed genetic system. Here, we report the development of a genetic system for the euryarchaeon IMPORTANCE: Species from all domains of life are infected by viruses. In some environments, viruses outnumber their microbial hosts by a factor of 10, and viruses are the most important predators of microorganisms. While much has been discovered about the infection mechanisms of bacterial and eukaryotic viruses, archaeal viruses remain understudied. Good model systems are needed to study their virus-host interactions in detail. The salt-loving archaeon

Indexed as

Archaeal ProteinsHaloferaxHaloferax volcaniiVirusesGene DeletionPromoter Regions, GeneticArchaeal Proteinsarchaeaarchaeal virusarchaellumgenetic systemHaloferaxmegaplasmid

Identifiers

PMID38470030
PMCPMC11022537
OpenAlexW4392715815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.