ArticleMovement disorders clinical practice2024
Gender Differences in Task Specific Dystonia: What Can we Learn from Musician's Dystonia?
Article in Movement disorders clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Botulinum Toxin Treatment in Musician's Dystonia: Long-Term-Effects and Influencing Factors.Toxins · 2026Article
- Genetic and therapeutic insights in musician's dystonia: a single-centre case series and narrative review.Acta neurologica Belgica · 2026Observational
- Divergent Recovery Paths in Musicians' Dystonia.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMusician's Dystonia (MD) is a task specific, focal dystonia which usually occurs only at the instrument. The pathophysiology is not fully understood, but several risk factors like over-practice and genetic predisposition are known. Interestingly, 80% of those affected are men, which stands in contrast to the gender distribution in other focal dystonias, such as cervical dystonia.
objectivesOur aim was to evaluate the difference in women and men with regard to risk factors leading to MD.
methodsWe investigated known risk factors for MD in a large cohort of 364 MD patients by retrospectively collecting data on practice behavior and family history.
resultsIn line with previous studies, we found a ratio of ~4:1 men to women. Age at onset of MD was significantly lower in women; however, subsequent analysis revealed that it was a positive family history (FH+) and not gender that was associated with a lower age at onset. Furthermore, we found that those with negative family history had accumulated more practice time until onset of MD.
conclusionsThese results imply that the earlier age at onset in women did not depend on gender but was due to the higher proportion of a positive family history. In contrast, men were less likely to have a positive family history, suggesting that genetic factors may not be the primary reason for the higher prevalence of MD in men. Instead, differences in practice behaviors between men and women may contribute to this gender disparity.
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