Evidence map›Paper›PMID 38469671›Full record

ArticleMagnetic resonance in medicine2024

Reduced cross-scanner variability using vendor-agnostic sequences for single-shell diffusion MRI.

Qiang Liu, Lipeng Ning, Imam Ahmed Shaik, Congyu Liao, Borjan Gagoski, Berkin Bilgic, William Grissom, Jon-Fredrik Nielsen, Maxim Zaitsev, Yogesh Rathi

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qiang LiuBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0009-0007-6818-0115
Lipeng NingBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Imam Ahmed ShaikBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Congyu LiaoDepartment of Radiology, Stanford University, Stanford, California, USA.ORCID 0000-0003-2270-276X
Borjan GagoskiDepartment of Radiology, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-3777-2621
Berkin BilgicDepartment of Radiology, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-9080-7865
William GrissomDepartment of Biomedical Engineering, Case School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Jon-Fredrik NielsenFunctional MRI Laboratory, Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.
Maxim ZaitsevDivision of Medical Physics, Department of Diagnostic and Interventional Radiology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Yogesh RathiBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Funding

Next generation in-vivo diffusion imaging at submillimeter resolutionR01MH116173 · NIMH · STANFORD UNIVERSITY · PI Yogesh Rathi, Kawin Setsompop · 2018 to 2026
$6.2M
Mapping the superficial white matter connectome of the human brain using ultra high resolution multi-contrast diffusion MRIR01MH125860 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI MAKRIS, NIKOLAOS, O'DONNELL, LAUREN JEAN · 2021 to 2025
$4.1M
A harmonized vendor-agnostic environment for multi-site functional MRI studiesU24NS120056 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jon-Fredrik Nielsen, Maxim Zaitsev · 2021 to 2026
$3.3M
Harmonizing data acquisition, reconstruction, and analysis for reproducible, cross-vendor, open source MRIR01EB032378 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI BILGIC, BERKIN, RATHI, YOGESH · 2022 to 2025
$2.7M
Mapping of the intrinsic and extrinsic cerebellar connectome at ultra high resolution with expert neuroanatomical curationR01MH132610 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI MAKRIS, NIKOLAOS, O'DONNELL, LAUREN JEAN · 2023 to 2025
$2.6M
Joint structural-and-functional MRI analysis for predicting electroconvulsive therapy response in major depressive disorderK01MH117346 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI NING, LIPENG · 2019 to 2023
$916k
NIBIB NIH HHS R01 EB032378NIBIB NIH HHS R01EB032378NIMH NIH HHS K01MH117346NIMH NIH HHS R01 MH116173NIMH NIH HHS R01MH116173NIMH NIH HHS R01 MH125860NIMH NIH HHS R01MH125860NIMH NIH HHS R01 MH132610NINDS NIH HHS U24 NS120056
6 · The paper itself

Abstract

purposeTo reduce the inter-scanner variability of diffusion MRI (dMRI) measures between scanners from different vendors by developing a vendor-neutral dMRI pulse sequence using the open-source vendor-agnostic Pulseq platform.

methodsWe implemented a standard EPI based dMRI sequence in Pulseq. We tested it on two clinical scanners from different vendors (Siemens Prisma and GE Premier), systematically evaluating and comparing the within- and inter-scanner variability across the vendors, using both the vendor-provided and Pulseq dMRI sequences. Assessments covered both a diffusion phantom and three human subjects, using standard error (SE) and Lin's concordance correlation to measure the repeatability and reproducibility of standard DTI metrics including fractional anisotropy (FA) and mean diffusivity (MD).

resultsIdentical dMRI sequences were executed on both scanners using Pulseq. On the phantom, the Pulseq sequence showed more than a 2.5× reduction in SE (variability) across Siemens and GE scanners. Furthermore, Pulseq sequences exhibited markedly reduced SE in-vivo, maintaining scan-rescan repeatability while delivering lower variability in FA and MD (more than 50% reduction in cortical/subcortical regions) compared to vendor-provided sequences.

conclusionThe Pulseq diffusion sequence reduces the cross-scanner variability for both phantom and in-vivo data, which will benefit multi-center neuroimaging studies and improve the reproducibility of neuroimaging studies.

Indexed as

BrainDiffusion Magnetic Resonance ImagingPhantoms, ImagingAdultAlgorithmsAnisotropyFemaleHumansImage Processing, Computer-AssistedMaleReproducibility of ResultsdMRIMRI harmonizationopen MRIopen‐sourcePulseqreproducibilityvendor‐agnostic

Identifiers

PMID38469671
PMCPMC11055665

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.