Evidence map›Paper›PMID 38469482›Full record

ArticleFrontiers in insect science2023

Gene silencing in adult

Elijah Carroll, Nitish Kunte, Erin McGraw, Sujan Gautam, Ryan Range, Jose A Noveron-Nunez, David W Held, L Adriana Avila

Open access · goldAbstract read
In one paragraph

Article in Frontiers in insect science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. A BeetleInsects · 2026
    Article
  3. Article
  4. Evaluation of dsRNA produced inFrontiers in insect science · 2026
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Elijah CarrollDepartment of Entomology and Plant Pathology, Auburn University, Auburn, AL, United States.
Nitish KunteDepartment of Biological Sciences, Auburn University, Auburn, AL, United States.
Erin McGrawDepartment of Biological Sciences, Auburn University, Auburn, AL, United States.
Sujan GautamDepartment of Biological Sciences, Auburn University, Auburn, AL, United States.
Ryan RangeDepartment of Biological Sciences, Auburn University, Auburn, AL, United States.
Jose A Noveron-NunezDepartment of Biological Sciences, Auburn University, Auburn, AL, United States.
David W HeldDepartment of Biological Sciences, Auburn University, Auburn, AL, United States.
L Adriana AvilaDepartment of Entomology and Plant Pathology, Auburn University, Auburn, AL, United States.
Auburn University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene silencing by feeding double-stranded (dsRNA) holds promise as a novel pest management strategy. Nonetheless, degradation of dsRNA in the environment and within the insect gut, as well as inefficient systemic delivery are major limitations to applying this strategy. Branched amphiphilic peptide capsules (BAPCs) complexed with dsRNA have been used to successfully target genes outside and inside the gut epithelium upon ingestion. This suggests that BAPCs can protect dsRNA from degradation in the gut environment and successfully shuttle it across gut epithelium. In this study, our objectives were to 1) Determine whether feeding on BAPC-dsRNA complexes targeting a putative peritrophin gene of

Indexed as

dsRNA (double-stranded RNA)Japanese beetlenanoparticlesoral deliverypest managementScarabaeidae

Identifiers

PMID38469482
PMCPMC10926504
OpenAlexW4382450557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.