Evidence map›Paper›PMID 38469309›Full record

ArticleFrontiers in immunology2024

Comparative analysis of swine leukocyte antigen gene diversity in Göttingen Minipigs.

Sabine E Hammer, Tereza Duckova, Monica Gociman, Sandra Groiss, Clara P S Pernold, Karolin Hacker, Lena Kasper, Julia Sprung, Maria Stadler, Andres Eskjær Jensen and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Sabine E HammerDepartment of Pathobiology, Immunology, University of Veterinary Medicine Vienna, Vienna, Austria.
Tereza DuckovaDepartment of Pathobiology, Immunology, University of Veterinary Medicine Vienna, Vienna, Austria.
Monica GocimanDepartment of Pathobiology, Immunology, University of Veterinary Medicine Vienna, Vienna, Austria.
Sandra GroissDepartment of Pathobiology, Immunology, University of Veterinary Medicine Vienna, Vienna, Austria.
Clara P S PernoldDepartment of Pathobiology, Immunology, University of Veterinary Medicine Vienna, Vienna, Austria.
Karolin HackerInstitute of Transfusion Medicine and Transplant Engineering, Hannover Medical School, Hannover, Germany.
Lena KasperMerck Healthcare KGaA, Darmstadt, Germany.
Julia SprungDepartment of Pathobiology, Immunology, University of Veterinary Medicine Vienna, Vienna, Austria.
Maria StadlerDepartment of Pathobiology, Immunology, University of Veterinary Medicine Vienna, Vienna, Austria.
Andres Eskjær JensenEllegaard Göttingen Minipigs A/S, Dalmose, Denmark.
Armin SaalmüllerDepartment of Pathobiology, Immunology, University of Veterinary Medicine Vienna, Vienna, Austria.
Nadine WenzelInstitute of Transfusion Medicine and Transplant Engineering, Hannover Medical School, Hannover, Germany.
Constanca FigueiredoInstitute of Transfusion Medicine and Transplant Engineering, Hannover Medical School, Hannover, Germany.
University of Veterinary Medicine Vienna · ATMedizinische Hochschule Hannover · DEMerck (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Worldwide, pigs represent economically important farm animals, also representing a preferred preclinical large animal model for biomedical studies. The need for swine leukocyte antigen (SLA) typing is increasing with the expanded use of pigs in translational research, infection studies, and for veterinary vaccine design. Göttingen Minipigs (GMP) attract increasing attention as valuable model for pharmacological studies and transplantation research. This study represents a first-time assessment of the SLA gene diversity in Göttingen Minipigs in combination with a comparative metadata analysis with commercial pig lines. As Göttingen Minipigs could harbor private as well as potential novel SLA allele combinations, future research projects would benefit from the characterization of their SLA background. In 209 Göttingen Minipigs, SLA class I (

Indexed as

Histocompatibility Antigens Class IHistocompatibility Antigens Class IIAnimalsHaplotypesHumansSwineSwine, MiniatureHistocompatibility Antigens Class IHistocompatibility Antigens Class IIswine leukocyte antigenanimal modelbiomedical research and developmentpolymorphismSus scrofaswine leukocyte antigen (SLA)transplantationxenograft

Identifiers

PMID38469309
PMCPMC10925748
OpenAlexW4392165595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.