Evidence map›Paper›PMID 38469307›Full record

ArticleFrontiers in immunology2024

Reduced toxicity matched sibling bone marrow transplant results in excellent outcomes for severe congenital neutropenia.

Joseph H Oved, Nora M Gibson, Kimberly Venella, Caitlin W Elgarten, Lisa Wray, Julia T Warren, Timothy S Olson

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. HAX1 inhibits apoptosis and promotes maturation of neutrophils.Cell communication and signaling : CCS · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Joseph H Oved *Division of Pediatric Transplantation & Cellular Therapies, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Nora M Gibson *Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Kimberly VenellaDivision of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Caitlin W ElgartenDivision of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Lisa WrayDivision of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Julia T WarrenDivision of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Timothy S OlsonDivision of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Children's Hospital of Philadelphia · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Severe congenital neutropenia (SCN) is caused by germline mutations, most commonly in

Indexed as

Graft vs Host DiseaseHematopoietic Stem Cell TransplantationNeutropeniaBone Marrow TransplantationBusulfanChildCongenital Bone Marrow Failure SyndromesCyclophosphamideGranulocyte Colony-Stimulating FactorHumansProspective StudiesSiblingsBusulfanCyclophosphamideGranulocyte Colony-Stimulating Factorbone marrow failurebusulfan and fludarabineconditioning regimenprimary immunodeficiencysevere congenital neutropeniastem cell transplant

Identifiers

PMID38469307
PMCPMC10925630
OpenAlexW4392145915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.