Evidence map›Paper›PMID 38469303›Full record

ArticleFrontiers in immunology2024

Gene-edited pigs: a translational model for human food allergy against alpha-Gal and anaphylaxis.

Ying Wang, Miriam Hils, Andrea Fischer, Florian Wölbing, Tilo Biedermann, Angelika Schnieke, Konrad Fischer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Pre-clinical strategies and emerging technologies driving advances in the alpha-gal syndrome.Allergology international : official journal of the Japanese Society of Allergology · 2025
    Review
  4. Molecular breeding of pigs in the genome editing era.Genetics, selection, evolution : GSE · 2025
    Review
  5. Review
  6. A review of CD4Veterinary immunology and immunopathology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ying WangChair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany.
Miriam HilsDepartment of Dermatology and Allergy Biederstein, School of Medicine, Technical University of Munich, Munich, Germany.
Andrea FischerChair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany.
Florian WölbingDepartment of Dermatology and Allergy Biederstein, School of Medicine, Technical University of Munich, Munich, Germany.
Tilo BiedermannDepartment of Dermatology and Allergy Biederstein, School of Medicine, Technical University of Munich, Munich, Germany.
Angelika SchniekeChair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany.
Konrad FischerChair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany.
Technical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of food allergy is rising and is estimated to approach 10%. Red meat allergy is the first known food allergy elicited by immunoglobulin E (IgE) antibodies recognizing a carbohydrate. Due to the loss of function of the alpha-1,3-galactosyltransferase (

Indexed as

AnaphylaxisFood HypersensitivityAnimalsGalactoseGene EditingHumansImmunoglobulin EImmunoglobulin GSwineGalactoseImmunoglobulin EImmunoglobulin Ganaphylaxis to α-Galintracutaneous sensitizationred meat allergytranslational pig modelα-Gal allergy

Identifiers

PMID38469303
PMCPMC10925645
OpenAlexW4392165511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.