Evidence map›Paper›PMID 38469294›Full record

ArticleFrontiers in immunology2024

Utilizing murine dendritic cell line DC2.4 to evaluate the immunogenicity of subunit vaccines

Lantian Lu, Wei Yang Kong, Jiahui Zhang, Farrhana Firdaus, James W Wells, Rachel J Stephenson, Istvan Toth, Mariusz Skwarczynski, Jazmina L Gonzalez Cruz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  3. Immunogenicity of Gene and Cell Therapies.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026
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  14. Automated Synthesis and Purification of Hydrophobic Peptides.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Lantian LuSchool of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia.
Wei Yang KongFaculty of Medicine, Frazer Institute, The University of Queensland, Woolloongabba, QLD, Australia.
Jiahui ZhangSchool of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia.
Farrhana FirdausSchool of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia.
James W WellsFaculty of Medicine, Frazer Institute, The University of Queensland, Woolloongabba, QLD, Australia.
Rachel J StephensonSchool of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia.
Istvan TothSchool of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia.
Mariusz SkwarczynskiSchool of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia.
Jazmina L Gonzalez CruzFaculty of Medicine, Frazer Institute, The University of Queensland, Woolloongabba, QLD, Australia.
The University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subunit vaccines hold substantial promise in controlling infectious diseases, due to their superior safety profile, specific immunogenicity, simplified manufacturing processes, and well-defined chemical compositions. One of the most important end-targets of vaccines is a subset of lymphocytes originating from the thymus, known as T cells, which possess the ability to mount an antigen-specific immune response. Furthermore, vaccines confer long-term immunity through the generation of memory T cell pools. Dendritic cells are essential for the activation of T cells and the induction of adaptive immunity, making them key for the

Indexed as

Antigen PresentationDendritic CellsAnimalsCD40 AntigensCytokinesMiceVaccines, SubunitCD40 AntigensCytokinesVaccines, SubunitDC2.4dendritic cell maturationdendritic cell uptakein vitro assaysubunit vaccine

Identifiers

PMID38469294
PMCPMC10925716
OpenAlexW4392165456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.