Evidence map›Paper›PMID 38469156›Full record

ArticleRheumatology advances in practice2024

Differences in management approaches for lupus nephritis within the UK.

Sara T Ibrahim, Christopher J Edwards, Michael R Ehrenstein, Bridget Griffiths, Caroline Gordon, Peter Hewins, David Jayne, Liz Lightstone, Zoe McLaren, Benjamin Rhodes and 2 more

Open access · goldAbstract read
In one paragraph

Article in Rheumatology advances in practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Guideline
  2. IgA2Cell reports. Medicine · 2025
    Trial
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 2 countries.

Sara T IbrahimRheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0001-7442-7902
Christopher J EdwardsNIHR Southampton Clinical Research Facility, University Hospital Southampton, Southampton, UK.ORCID https://orcid.org/0000-0002-8233-6602
Michael R EhrensteinDepartment of Rheumatology, University College London, London, UK.ORCID https://orcid.org/0000-0003-1673-743X
Bridget GriffithsDepartment of Rheumatology, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Caroline GordonRheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0002-1244-6443
Peter HewinsDepartment of Renal Medicine, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
David JayneDepartment of Medicine, University of Cambridge, Cambridge, UK.
Liz LightstoneCentre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London, UK.
Zoe McLarenDepartment of Rheumatology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Benjamin RhodesRheumatology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Edward M VitalLeeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.ORCID https://orcid.org/0000-0003-1637-4755
John A ReynoldsRheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0002-8962-4404
Sandwell & West Birmingham Hospitals NHS Trust · GBUniversity Hospitals Birmingham NHS Foundation Trust · GBImperial College London · GBNewcastle upon Tyne Hospitals NHS Foundation Trust · GBUniversity College London · GBUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Birmingham · GBUniversity of Cambridge · GBUniversity of Leeds · GBUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Outcomes of therapy for LN are often suboptimal. Guidelines offer varied options for treatment of LN and treatment strategies may differ between clinicians and regions. We aimed to assess variations in the usual practice of UK physicians who treat LN. Methods: We conducted an online survey of simulated LN cases for UK rheumatologists and nephrologists to identify treatment preferences for class IV and class V LN. Results: Of 77 respondents, 48 (62.3%) were rheumatologists and 29 (37.7%) were nephrologists. A total of 37 (48.0%) reported having a joint clinic between nephrologists and rheumatologists, 54 (70.0%) reported having a multidisciplinary team meeting for LN and 26 (33.7%) reported having a specialized lupus nurse. Of the respondents, 58 (75%) reported arranging a renal biopsy before starting the treatment. A total of 20 (69%) of the nephrologists, but only 13 (27%) rheumatologists, reported having a formal departmental protocol for treating patients with LN ( Conclusion: There was variation in the use of protocols, specialist clinic service provision, biopsies and primary and secondary treatment choices for LN reported by nephrologists and rheumatologists in the UK.

Indexed as

lupus nephritisrefractorytreatmentUK

Identifiers

PMID38469156
PMCPMC10926897
OpenAlexW4391675951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.