Evidence map›Paper›PMID 38469065›Full record

ArticleSleep and biological rhythms2022

Genome-wide association study of idiopathic hypersomnia in a Japanese population.

Kotomi Tanida, Mihoko Shimada, Seik-Soon Khor, Hiromi Toyoda, Kayoko Kato, Nozomu Kotorii, Tatayu Kotorii, Yu Ariyoshi, Takao Kato, Hiroshi Hiejima and 23 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sleep and biological rhythms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Current knowledge on the pathophysiology of idiopathic hypersomnia and potential mechanisms of action for low-sodium oxybate treatment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 13 institutions in 1 country.

Kotomi TanidaDepartment of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Mihoko ShimadaDepartment of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Seik-Soon KhorDepartment of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hiromi ToyodaDepartment of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Kayoko KatoDepartment of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Nozomu KotoriiDepartment of Neuropsychiatry, Kurume University School of Medicine, Fukuoka, Japan.
Tatayu KotoriiKotorii Isahaya Hospital, Nagasaki, Japan.
Yu AriyoshiAriyoshi Sleep Clinic, Fukuoka, Japan.
Takao KatoDepartment of Neuropsychiatry, Kurume University School of Medicine, Fukuoka, Japan.
Hiroshi HiejimaDepartment of Neuropsychiatry, Kurume University School of Medicine, Fukuoka, Japan.
Motohiro OzoneDepartment of Neuropsychiatry, Kurume University School of Medicine, Fukuoka, Japan.
Naohisa UchimuraDepartment of Neuropsychiatry, Kurume University School of Medicine, Fukuoka, Japan.
Azusa IkegamiSleep Center, Kuwamizu Hospital, Kumamoto, Japan.
Kazuhiko KumeSleep Center, Kuwamizu Hospital, Kumamoto, Japan.
Takashi KanbayashiInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Ibaraki, Japan.
Aya ImanishiDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita, Japan.
Yuichi KameiDepartment of Laboratory Medicine, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan.
Akiko HidaDepartment of Sleep-Wake Disorders, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
Yamato WadaDepartment of Psychiatry, Hannan Hospital, Osaka, Japan.
Kenji KurodaDepartment of Psychiatry, Hannan Hospital, Osaka, Japan.
Masayuki MiyamotoDepartment of Neurology, Dokkyo Medical University, Tochigi, Japan.
Koichi HirataDepartment of Neurology, Dokkyo Medical University, Tochigi, Japan.
Masanori TakamiDepartment of Psychiatry, Shiga University of Medical Science, Shiga, Japan.
Naoto YamadaDepartment of Psychiatry, Shiga University of Medical Science, Shiga, Japan.
Masako OkawaDepartment of Sleep Medicine, Shiga University of Medical Science, Shiga, Japan.
Naoto OmataDepartment of Nursing, Faculty of Health Science, Fukui Health Science University, Fukui, Japan.
Hideaki KondoInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Ibaraki, Japan.
Tohru KodamaSleep Disorders Project, Department of Psychiatry and Behavioral Sciences, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo, 156-8506 Japan.
Yuichi InoueDepartment of Somnology, Tokyo Medical University, Tokyo, Japan.
Kazuo MishimaInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Ibaraki, Japan.
Makoto HondaSleep Disorders Project, Department of Psychiatry and Behavioral Sciences, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo, 156-8506 Japan.
Katsushi TokunagaDepartment of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Taku MiyagawaDepartment of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID 0000-0002-9466-9420
Kurume University · JPTokyo Institute of Psychiatry · JPThe University of Tokyo · JPUniversity of Tsukuba · JPDokkyo Medical University · JPHannan University · JPNational Center for Global Health and Medicine · JPNational Center of Neurology and Psychiatry · JPShiga University of Medical Science · JPTokyo Medical University · JPAkita University · JPNagoya City University · JPUniversity of Fukui · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic hypersomnia (IH) is a rare sleep disorder characterized by excessive daytime sleepiness, great difficulty upon awakening, and prolonged sleep time. In contrast to narcolepsy type 1, which is a well-recognized hypersomnia, the etiology of IH remains poorly understood. No susceptibility loci for IH have been identified, although familial aggregations have been observed among patients with IH. Narcolepsy type 1 is strongly associated with human leukocyte antigen Supplementary Information: The online version contains supplementary material available at 10.1007/s41105-021-00349-2.

Indexed as

Genome-wide association study (GWAS)Idiopathic hypersomniaPhosphodiesteraseSingle-nucleotide polymorphisms (SNPs)Sleep

Identifiers

PMID38469065
PMCPMC10899960
OpenAlexW3206276386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.