Evidence map›Paper›PMID 38468650›Full record

ArticleSurgical neurology international2024

Essentials for early diagnosis of primary intramedullary spinal cord lymphoma. How to suspect primary intramedullary spinal cord lymphoma early and proceed to invasive biopsy? A case report and literature review.

Seiji Shigekawa, Akihiro Inoue, Yukihiro Miyazaki, Mashio Taniwaki, Kota Kanehisa, Sayaka Matsumoto, Yoko Okada, Riko Kitazawa, Takeharu Kunieda

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Surgical neurology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Primary spinal cord malignant B-cell lymphoma successfully treated with tirabrutinib at relapse: a case report.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Seiji ShigekawaDepartment of Neurosurgery, Ehime University School of Medicine, Toon, Japan.
Akihiro InoueDepartment of Neurosurgery, Ehime University School of Medicine, Toon, Japan.
Yukihiro MiyazakiDepartment of Hematology, Clinical Immunology and Infectious Diseases, Ehime University School of Medicine, Toon, Japan.
Mashio TaniwakiDivision of Diagnostic Pathology, Ehime University School of Medicine, Toon, Japan.
Kota KanehisaDepartment of Neurosurgery, Ehime University School of Medicine, Toon, Japan.
Sayaka MatsumotoDepartment of Neurology and Geriatric Medicine, Ehime University School of Medicine, Toon, Japan.
Yoko OkadaDepartment of Neurology and Geriatric Medicine, Ehime University School of Medicine, Toon, Japan.
Riko KitazawaDivision of Diagnostic Pathology, Ehime University School of Medicine, Toon, Japan.
Takeharu KuniedaDepartment of Neurosurgery, Ehime University School of Medicine, Toon, Japan.
Ehime University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Primary intramedullary spinal cord lymphoma (PISCL) is an extremely rare condition. Early diagnosis is very difficult due to the nonspecific clinical and imaging findings. A biopsy is essential for a definitive diagnosis, but courage is required to perform the surgery. Here, we present a case of PISCL and suggest useful indicators for accurate diagnosis of this pathological entity. Case Description: A 70-year-old woman presented with subacute bilateral lower-limb paralysis, disturbance of warm and pain sensations, and vesicorectal disturbance. Magnetic resonance imaging showed a contrast-enhanced mass from C7 to Th2 and large, edematous lesions from the upper cervical to lower thoracic spinal cord. Elevated uptake of Conclusion: In cases with poor response to treatment and a progressive course, PISCL should be considered, and spinal cord biopsy should be performed if PET shows increased

Indexed as

Accurate diagnosisPositron emission tomographyPrimary intramedullary spinal cord lymphomaSurgical biopsyβ2-microglobulin

Identifiers

PMID38468650
PMCPMC10927179
OpenAlexW4391684621

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.