ArticleSleep and biological rhythms2022
The relationship between high-density lipoprotein cholesterol and overall sleep quality in the adult population with asthma.
Article in Sleep and biological rhythms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.
- Pooled it
- Mediating role of basophils in the triacylglycerol-asthma link: a Mendelian randomization study.3 Biotech · 2025Article
- HDL and sleep: beyond cardiovascular diseases and allergy.Sleep and biological rhythms · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous basic studies have shown that high-density lipoprotein cholesterol (HDL-C) has anti-inflammatory effects that protect against asthma. Our study was aimed at examining the association between blood lipid levels and sleep quality in the adult population with asthma. We evaluated the blood lipid levels and sleep scores of 1013 adult participants in the Midlife in the United States (MIDUS) study to investigate the association of lipid levels with overall sleep quality using linear regression models in subjects with asthma and without asthma, respectively. In a total of 1013 participants (with asthma = 127 and without asthma = 886) included in our study, participants with asthma had poor sleep quality, compared with participants without asthma. Moreover, our smooth curves suggested that blood HDL-C and triglyceride levels, rather than total cholesterol and low-density lipoprotein cholesterol (LDL-C), were significantly associated with global sleep score. Multivariate correction models were used to further evaluate blood lipid profiles and the overall sleep quality. We observed that only blood HDL-C levels were still negatively and independently associated with global sleep score in participants with asthma (
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