Evidence map›Paper›PMID 38468516›Full record

ReviewCurrent medicinal chemistry2025

Regulating Triplet Excitons of Organic Luminophores for Promoted Bioimaging.

Zhipeng Zhao, Rui Du, Xiaodi Feng, Zhengshuo Wang, Tianjie Wang, Zongzhao Xie, Hua Yuan, Yeqiang Tan, Hanlin Ou

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhipeng ZhaoState Key Laboratory of Bio-Fibers and Eco-Textiles, Collaborative Innovation Center of Marine Biobased Fiber and Ecological Textile Technology, College of Materials Science and Engineering, Qingdao University, No. 308, Ningxia Rd., Shinan District, Qingdao, 266071, China.
Rui DuState Key Laboratory of Bio-Fibers and Eco-Textiles, Collaborative Innovation Center of Marine Biobased Fiber and Ecological Textile Technology, College of Materials Science and Engineering, Qingdao University, No. 308, Ningxia Rd., Shinan District, Qingdao, 266071, China.
Xiaodi FengQingdao Hiser Hospital Affiliated to Qingdao University (Qingdao Traditional Chinese Medicine Hospital), No. 4, Renmin Rd., Shibei District, Qingdao, 266033, China.
Zhengshuo WangState Key Laboratory of Bio-Fibers and Eco-Textiles, Collaborative Innovation Center of Marine Biobased Fiber and Ecological Textile Technology, College of Materials Science and Engineering, Qingdao University, No. 308, Ningxia Rd., Shinan District, Qingdao, 266071, China.
Tianjie WangState Key Laboratory of Bio-Fibers and Eco-Textiles, Collaborative Innovation Center of Marine Biobased Fiber and Ecological Textile Technology, College of Materials Science and Engineering, Qingdao University, No. 308, Ningxia Rd., Shinan District, Qingdao, 266071, China.
Zongzhao XieState Key Laboratory of Bio-Fibers and Eco-Textiles, Collaborative Innovation Center of Marine Biobased Fiber and Ecological Textile Technology, College of Materials Science and Engineering, Qingdao University, No. 308, Ningxia Rd., Shinan District, Qingdao, 266071, China.
Hua YuanState Key Laboratory of Bio-Fibers and Eco-Textiles, Collaborative Innovation Center of Marine Biobased Fiber and Ecological Textile Technology, College of Materials Science and Engineering, Qingdao University, No. 308, Ningxia Rd., Shinan District, Qingdao, 266071, China.
Yeqiang TanState Key Laboratory of Bio-Fibers and Eco-Textiles, Collaborative Innovation Center of Marine Biobased Fiber and Ecological Textile Technology, College of Materials Science and Engineering, Qingdao University, No. 308, Ningxia Rd., Shinan District, Qingdao, 266071, China.
Hanlin OuState Key Laboratory of Bio-Fibers and Eco-Textiles, Collaborative Innovation Center of Marine Biobased Fiber and Ecological Textile Technology, College of Materials Science and Engineering, Qingdao University, No. 308, Ningxia Rd., Shinan District, Qingdao, 266071, China.

Funding

National Natural Science Foundation of China U22A20250, U21A2097, U22A20131, 52072193, 52361165657Shandong Provincial Natural Science Foundation ZR2021JQ16Support Plan on Science and Technology for Youth Innovation of Universities in Shandong Province 2023KJ230
6 · The paper itself

Abstract

Afterglow materials with organic room temperature phosphorescence (RTP) or thermally activated delayed fluorescence (TADF) exhibit significant potential in biological imaging due to their long lifetime. By utilizing time-resolved technology, interference from biological tissue fluorescence can be mitigated, enabling high signal-tobackground ratio imaging. Despite the continued emergence of individual reports on RTP or TADF in recent years, comprehensive reviews addressing these two materials are rare. Therefore, this review aims to provide a comprehensive overview of several typical molecular designs for organic RTP and TADF materials. It also explores the primary methods through which triplet excitons resist quenching by water and oxygen. Furthermore, we analyze the principal challenges faced by afterglow materials and discuss key directions for future research with the hope of inspiring developments in afterglow imaging.

Indexed as

Fluorescent DyesOptical ImagingAnimalsHumansFluorescent DyesAfterglow bioimagingintersystem crossingroom temperature phosphorescencetherapeutic technologies.thermally activated delayed fluorescencetriplet excited states

Identifiers

PMID38468516

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.