Evidence map›Paper›PMID 38468395›Full record

Trial reportJournal of clinical laboratory analysis2024

Exploration of the Clinical Effect of Different Autotransfusion Methods on Patients With Femoral Shaft Fracture Surgery.

Yujia Wang, Huan Wang, Jiaming Xu, Jinhuo Wang, Laiwei You, Yu Bai, Jianrong Guo

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of clinical laboratory analysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yujia WangSchool of Gongli Hospital Medical Technology, University of Shanghai for Science and Technology, Shanghai, China.
Huan WangDepartment of Anesthesiology, Shanghai Gongli Hospital, Naval Military Medical University, Shanghai, China.
Jiaming XuDepartment of Anesthesiology, Shanghai Gongli Hospital, Naval Military Medical University, Shanghai, China.
Jinhuo WangDepartment of Anesthesiology, Shanghai Gongli Hospital, Naval Military Medical University, Shanghai, China.
Laiwei YouDepartment of Anesthesiology, Shanghai Gongli Hospital, Naval Military Medical University, Shanghai, China.
Yu BaiDepartment of Anesthesiology, Shanghai Gongli Hospital, Naval Military Medical University, Shanghai, China.
Jianrong GuoDepartment of Anesthesiology, Shanghai Gongli Hospital, Naval Military Medical University, Shanghai, China.ORCID https://orcid.org/0000-0002-1855-1762
Second Military Medical University · CNUniversity of Shanghai for Science and Technology · CN

Funding

Key Disciplines Group Construction Project of Pudong Health Bureau of Shanghai PWZxq2022-5
6 · The paper itself

Abstract

objectiveTo explore the clinical effect of predeposit, salvage, and hemodilution autotransfusion on patients with femoral shaft fracture (FSF) surgery.

methodsSelected patients with FSF were randomly divided into three groups: intraoperative blood salvage autotransfusion, preoperative hemodilution autohemotransfusion, and predeposit autotransfusion. Five days after the operation, the body temperature, heart rate, blood platelet (PLT), and hemoglobin (Hb) of patients were determined. The concentrations of EPO and GM-CSF in the three groups were calculated by ELISA. The content of CD14+ monocytes was calculated by FCM assay. The growth time and condition of the patient's callus were determined at the 30th, 45th, and 60th day after operation. Cox regression analysis was used to analyze the correlation between EPO, GM-CSF, CD14+ mononuclear content, callus growth, and autotransfusion methods.

resultsThere were no statistically significant differences in body temperature and heart rate between the three groups (p > 0.05). PLT and Hb in the Predeposit group were markedly increased compared with that in the Salvage and Hemodilution groups. The concentrations of EPO and GM-CSF in the Predeposit group were markedly increased compared with that in the Salvage and Hemodilution groups. The content of CD14+ monocytes in the Predeposit group was significantly higher than that in the Salvage and Hemodilution groups. Predeposit autotransfusion promotes callus growth more quickly.

conclusionPredeposit autotransfusion promoted the recovery of patients with FSF after the operation more quickly than salvage autotransfusion and hemodilution autotransfusion.

Indexed as

Blood Transfusion, AutologousGranulocyte-Macrophage Colony-Stimulating FactorBiological AssayHemodilutionHemoglobinsHumansGranulocyte-Macrophage Colony-Stimulating FactorHemoglobinsautotransfusionfemoral shaft fracture (FSF)hemodilutionpredepositsalvage

Identifiers

PMID38468395
PMCPMC10959180
OpenAlexW4392714628

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.