Evidence map›Paper›PMID 38467696›Full record

ArticleScientific reports2024

Evidence for disrupted copper availability in human spinal cord supports Cu

James B W Hilton, Kai Kysenius, Jeffrey R Liddell, Stephen W Mercer, Bence Paul, Joseph S Beckman, Catriona A McLean, Anthony R White, Paul S Donnelly, Ashley I Bush and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 36 citations in OpenAlex.

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  20. Integrated elemental analysis supports targeting copper perturbations as a therapeutic strategy in multiple sclerosis.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

James B W HiltonDepartment of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia.ORCID http://orcid.org/0000-0002-2657-3566
Kai KyseniusDepartment of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia.
Jeffrey R LiddellDepartment of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia.ORCID http://orcid.org/0000-0002-0798-5338
Stephen W MercerDepartment of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia.
Bence PaulSchool of Geography, Earth and Atmospheric Sciences, The University of Melbourne, Victoria, 3010, Australia.
Joseph S BeckmanLinus Pauling Institute and Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR, 97331, USA.
Catriona A McLeanDepartment of Anatomical Pathology, The Alfred Hospital, Victoria, 3004, Australia.
Anthony R WhiteMental Health Program, Department of Cell and Molecular Biology, Queensland Institute of Biomedical Research Berghofer, Herston, QLD, 4006, Australia.
Paul S DonnellySchool of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria, 3010, Australia.
Ashley I BushMelbourne Dementia Research Centre, The University of Melbourne and Florey Institute of Neuroscience and Mental Health, Victoria, 3010, Australia.
Dominic J HareAtomic Medicine Initiative, University of Technology Sydney, Ultimo, NSW, 2007, Australia.
Blaine R RobertsDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Peter J CrouchDepartment of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia. pjcrouch@unimelb.edu.au.ORCID http://orcid.org/0000-0002-7777-4747
The University of Melbourne · AUEmory University · USOregon State University · USQIMR Berghofer Medical Research Institute · AUThe Alfred Hospital · AUUniversity of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The copper compound Cu

Indexed as

Amyotrophic Lateral SclerosisCoordination ComplexesNeurodegenerative DiseasesThiosemicarbazonesAnimalsCeruloplasminCopperDisease Models, AnimalHumansMiceMice, TransgenicSpinal CordSuperoxide DismutaseSuperoxide Dismutase-1CeruloplasminCoordination ComplexesCoppercopper (II) diacetyl-di(N(4)-methylthiosemicarbazone)Superoxide DismutaseSuperoxide Dismutase-1Thiosemicarbazones

Identifiers

PMID38467696
PMCPMC10928073
OpenAlexW4392663667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.