Evidence map›Paper›PMID 38467570›Full record

ArticlePhysiological reports2024

Cervical spinal cord hemisection impacts sigh and the respiratory reset in male rats.

Matthew J Fogarty, Wen-Zhi Zhan, Carlos B Mantilla, Gary C Sieck

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Matthew J FogartyDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0003-0128-7042
Wen-Zhi ZhanDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
Carlos B MantillaDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
Gary C SieckDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
Mayo Clinic · US

Funding

Respiratory Control in Old AgeR01AG044615 · NIA · MAYO CLINIC ROCHESTER · PI MANTILLA, CARLOS B, SIECK, GARY C. · 2013 to 2025
$6.9M
Enhancing Respiratory Motor Function after Spinal Cord InjuryR01HL146114 · NHLBI · MAYO CLINIC ROCHESTER · PI Carlos B Mantilla, Gary C. Sieck · 2019 to 2026
$5.4M
Ameliorating Synaptic and Mitochondrial Dysfunctions of the Respiratory Neuromotor System in Alzheimer's DiseaseR56HL166204 · NHLBI · MAYO CLINIC ROCHESTER · PI FOGARTY, MATTHEW · 2023 to 2023
$532k
NHLBI NIH HHS R01 HL146114NHLBI NIH HHS R56 HL166204NIA NIH HHS R01 AG044615
6 · The paper itself

Abstract

Cervical spinal cord injury impacts ventilatory and non-ventilatory functions of the diaphragm muscle (DIAm) and contributes to clinical morbidity and mortality in the afflicted population. Periodically, integrated brainstem neural circuit activity drives the DIAm to generate a markedly augmented effort or sigh-which plays an important role in preventing atelectasis and thus maintaining lung function. Across species, the general pattern of DIAm efforts during a normal sigh is variable in amplitude and the extent of post-sigh "apnea" (i.e., the post-sigh inter-breath interval). This post-sigh inter-breath interval acts as a respiratory reset, following the interruption of regular respiratory rhythm by sigh. We examined the impact of upper cervical (C

Indexed as

Cervical CordSpinal Cord InjuriesAnimalsDiaphragmMaleRatsRats, Sprague-DawleyRespirationdiaphragmrespirationspinal cordtransdiaphragmatic pressureventilation

Identifiers

PMID38467570
PMCPMC10927604
OpenAlexW4392713431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.