Evidence map›Paper›PMID 38467429›Full record

ArticleJournal of the American Board of Family Medicine : JABFM2024

Drug Deactivation Pouches for Primary Prevention of Opioid Overdose: Perceptions and Attitudes of Community Members.

Ayodeji Otufowora, Kathleen L Egan, Piyush V Chaudhari, Aderonke A Okusanya, Afeez O Ogidan, Linda B Cottler

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Board of Family Medicine : JABFM, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ayodeji OtufoworaFrom the Department of Pediatrics, Columbia University Medical Center, Columbia University, New York, NY (AO), Department of Implementation Science, Division of Public Health Sciences, Wake Forest University School of Medicine, NC (KLE), Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL (PVC), Department of Pharmacy, College of Pharmacy and Health Sciences, Western New England University, Springfield, MA (AAO), Department of Medicine & Surgery, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu campus, Ogun State, Nigeria (AOO), Department of Epidemiology, College of Public Health and Health Professions, College of Medicine, University of Florida, Gainesville, FL(LBC). ao2895@cumc.columbia.edu.
Kathleen L EganFrom the Department of Pediatrics, Columbia University Medical Center, Columbia University, New York, NY (AO), Department of Implementation Science, Division of Public Health Sciences, Wake Forest University School of Medicine, NC (KLE), Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL (PVC), Department of Pharmacy, College of Pharmacy and Health Sciences, Western New England University, Springfield, MA (AAO), Department of Medicine & Surgery, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu campus, Ogun State, Nigeria (AOO), Department of Epidemiology, College of Public Health and Health Professions, College of Medicine, University of Florida, Gainesville, FL(LBC).
Piyush V ChaudhariFrom the Department of Pediatrics, Columbia University Medical Center, Columbia University, New York, NY (AO), Department of Implementation Science, Division of Public Health Sciences, Wake Forest University School of Medicine, NC (KLE), Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL (PVC), Department of Pharmacy, College of Pharmacy and Health Sciences, Western New England University, Springfield, MA (AAO), Department of Medicine & Surgery, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu campus, Ogun State, Nigeria (AOO), Department of Epidemiology, College of Public Health and Health Professions, College of Medicine, University of Florida, Gainesville, FL(LBC).
Aderonke A OkusanyaFrom the Department of Pediatrics, Columbia University Medical Center, Columbia University, New York, NY (AO), Department of Implementation Science, Division of Public Health Sciences, Wake Forest University School of Medicine, NC (KLE), Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL (PVC), Department of Pharmacy, College of Pharmacy and Health Sciences, Western New England University, Springfield, MA (AAO), Department of Medicine & Surgery, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu campus, Ogun State, Nigeria (AOO), Department of Epidemiology, College of Public Health and Health Professions, College of Medicine, University of Florida, Gainesville, FL(LBC).
Afeez O OgidanFrom the Department of Pediatrics, Columbia University Medical Center, Columbia University, New York, NY (AO), Department of Implementation Science, Division of Public Health Sciences, Wake Forest University School of Medicine, NC (KLE), Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL (PVC), Department of Pharmacy, College of Pharmacy and Health Sciences, Western New England University, Springfield, MA (AAO), Department of Medicine & Surgery, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu campus, Ogun State, Nigeria (AOO), Department of Epidemiology, College of Public Health and Health Professions, College of Medicine, University of Florida, Gainesville, FL(LBC).
Linda B CottlerFrom the Department of Pediatrics, Columbia University Medical Center, Columbia University, New York, NY (AO), Department of Implementation Science, Division of Public Health Sciences, Wake Forest University School of Medicine, NC (KLE), Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL (PVC), Department of Pharmacy, College of Pharmacy and Health Sciences, Western New England University, Springfield, MA (AAO), Department of Medicine & Surgery, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu campus, Ogun State, Nigeria (AOO), Department of Epidemiology, College of Public Health and Health Professions, College of Medicine, University of Florida, Gainesville, FL(LBC).
Columbia University · US

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
UF Clinical and Translational Science AwardUL1TR000064 · NCATS · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2012 to 2014
$12.2M
UF Substance Abuse Training Center in Public HealthT32DA035167 · NIDA · UNIVERSITY OF FLORIDA · PI Linda B. Cottler · 2014 to 2026
$4.8M
NCATS NIH HHS UL1 TR000064NCATS NIH HHS UL1 TR001427NIDA NIH HHS T32 DA035167
6 · The paper itself

Abstract

importanceA substantial number of opioid analgesics dispensed into communities will go unused and be susceptible to diversion for misuse. Convenient, efficient, and environmentally safe mechanisms for disposal are needed to prevent the diversion of unused opioid analgesics.

objectiveThis initiative piloted the feasibility of distributing drug deactivation pouches in a community setting and examined community members' acceptance, intention to use drug deactivation pouches, and their current disposal practices of unused opioid analgesics. Although many studies have examined the benefits of deactivation pouches in preventing drug overdose, few have explored community members' perspectives, the feasibility, and the acceptability of these pouches in disposing of unused medications.

methodsIn the fall of 2017, we piloted the distribution of drug deactivation pouches to assess the overall interest in the pouches at a 3-day community event and continued the second wave of this pilot in the community from the summer of 2018 to the spring of 2019.Our main outcomes and measures included the acceptance of the drug deactivation pouches and the intention to use the pouches. "Acceptance" was defined as study participants physically taking the kit and "Intention" was how participants intended to use the pouch.

resultsA total of 170 community members were approached at a community event about the drug deactivation pouches and 116 accepted at least 1 pouch (68.2% acceptance rate). In the second wave, 124 community members were approached by Community Health Workers; 100% accepted the pouch. Overall, the acceptance rate was 81.6%. People mentioned significant interest in using the pouches. Furthermore, surveys that assessed community members' intention to use the deactivation pouches showed that 48% intended to use the pouch. CONCLUSIONS AND RELEVANCE: The distribution of drug deactivation pouches is feasible in a community setting and although community members expressed interest in using drug deactivation pouches to dispose of unused opioid analgesics and other drugs, the majority still disposed of their unused medications through other avenues. This, underscore the need to raise community members' awareness about the importance, benefits, and viability of these pouches as a tool for the primary prevention of opioid overdose because of their ease of use, safety, environmental considerations, and cost-effectiveness.

Indexed as

Drug OverdoseOpiate OverdoseAnalgesics, OpioidHumansPrimary PreventionSurveys and QuestionnairesAnalgesics, OpioidDrug Deactivation PouchesDrug OverdoseFeasibility StudiesFloridaIntentionOpioidsSubstance-Related Disorders

Identifiers

PMID38467429
PMCPMC11491157
OpenAlexW4392668651

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.