Evidence map›Paper›PMID 38467135›Full record

ArticleThe lancet. HIV2024

Progress towards the UNAIDS 95-95-95 targets in the Fifth Botswana AIDS Impact Survey (BAIS V 2021): a nationally representative survey.

Madisa Mine, Kristen A Stafford, Rebecca L Laws, Reson Marima, Phenyo Lekone, Dinah Ramaabya, Kgomotso Makhaola, Hetal K Patel, Prichard Mapondera, Floris Wray-Gordon and 21 more

Abstract read
In one paragraph

Article in The lancet. HIV, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  9. Global Measures of HIV Care Accessibility Across Urban, Suburban, and Rural Areas.Journal of urban health : bulletin of the New York Academy of Medicine · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

31 authors.

Madisa MineMinistry of Health, Gaborone, Botswana.
Kristen A StaffordCenter for International Health, Education, and Biosecurity, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Rebecca L LawsDivision of Global HIV and TB, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Reson MarimaBotswana University of Maryland School of Medicine Health Initiative (Bummhi), Gaborone, Botswana.
Phenyo LekoneDivision of Global HIV and TB, US Centers for Disease Control and Prevention, Gaborone, Botswana.
Dinah RamaabyaMinistry of Health, Gaborone, Botswana.
Kgomotso MakhaolaDivision of Global HIV and TB, US Centers for Disease Control and Prevention, Gaborone, Botswana.
Hetal K PatelDivision of Global HIV and TB, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Prichard MaponderaBotswana University of Maryland School of Medicine Health Initiative (Bummhi), Gaborone, Botswana.
Floris Wray-GordonDivision of Global HIV and TB, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Chinedu AgbakwuruCenter for International Health, Education, and Biosecurity, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Lillian OkuiBotswana University of Maryland School of Medicine Health Initiative (Bummhi), Gaborone, Botswana.
Susan MatroosStatistics Botswana, Gaborone, Botswana.
Eden OnyadileStatistics Botswana, Gaborone, Botswana.
Julia NgidiMinistry of Health, Gaborone, Botswana.
Alash'le AbimikuCenter for International Health, Education, and Biosecurity, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Khuteletso BagapiDivision of Global HIV and TB, US Centers for Disease Control and Prevention, Gaborone, Botswana.
Bornapate NkomoMinistry of Health, Gaborone, Botswana.
Stephane M BodikaDivision of Global HIV and TB, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Kaylee J KimDivision of Global HIV and TB, US Centers for Disease Control and Prevention, Gaborone, Botswana.
Mirna MoloneyCenter for International Health, Education, and Biosecurity, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Andrew MitchellCenter for International Health, Education, and Biosecurity, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Akipu EhocheCenter for International Health, Education, and Biosecurity, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Faith L UsseryDivision of Global HIV and TB, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Steven Y HongDivision of Global HIV and TB, US Centers for Disease Control and Prevention, Gaborone, Botswana.
Stella KeipeileNational AIDS and Health Promotion Agency, Gaborone, Botswana.
Matshelo MatlhagaNational AIDS and Health Promotion Agency, Gaborone, Botswana.
Rapetse MathumoNational AIDS and Health Promotion Agency, Gaborone, Botswana.
Robert SelatoNational AIDS and Health Promotion Agency, Gaborone, Botswana.
Manhattan E CharuratCenter for International Health, Education, and Biosecurity, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Andrew C VoetschDivision of Global HIV and TB, US Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: avoetsch@cdc.gov.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundIn 2014, UNAIDS set a goal to end the AIDS epidemic by achieving targets for the percentage of people living with HIV who were aware of their status, on antiretroviral therapy (ART), and virally suppressed. In 2020, these targets were revised to 95% for each measure (known as 95-95-95), to be reached among people living with HIV by 2025. We used data from the Fifth Botswana AIDS Impact Survey (BAIS V) to measure progress towards these testing and treatment targets in Botswana.

methodsBAIS V used a two-stage cluster design to obtain a nationally representative sample of people aged 15-64 years in Botswana. During March-August, 2021, 14 763 consenting participants were interviewed and tested for HIV in their households by survey teams. HIV-positive specimens were tested for viral load, presence of antiretroviral drugs, and recency of infection using the HIV-1 limiting antigen avidity enzyme immunoassay. Estimates of HIV-positive status and use of ART were based on self-report and the analysis of blood specimens for antiretroviral drugs. Viral load suppression was defined as an HIV RNA concentration of less than 1000 copies per mL. HIV incidence was calculated using the recent infection testing algorithm. Data were weighted to account for the complex survey design.

findingsThe national HIV prevalence in Botswana among people aged 15-64 years was 20·8% and the annual incidence of HIV infection was 0·2%. 95·1% (men 93·0%, women 96·4%) of people living with HIV aged 15-64 years were aware of their status, 98·0% (men 97·2%, women 98·4%) of those aware were on ART, and 97·9% (men 96·6%, women 98·6%) of those on ART had viral load suppression. Among young people (aged 15-24 years) living with HIV, 84·5% were aware of their status, 98·5% of those aware were on ART, and 91·6% of those on ART had viral load suppression. The prevalance of viral load suppression among all people living with HIV was 91·8%, and varied by district-ranging from 85·3% in Gaborone to 100·0% in Selibe Phikwe.

interpretationBAIS V is the first population-based survey worldwide to report the achievement of the UNAIDS 95-95-95 goals, both overall and among women. Strategies to reach undiagnosed men and young people, including young women, are needed.

fundingUS President's Emergency Plan for AIDS Relief.

Indexed as

Acquired Immunodeficiency SyndromeHIV InfectionsAdolescentAnti-Retroviral AgentsBotswanaFemaleHumansMalePrevalenceSurveys and QuestionnairesViral LoadAnti-Retroviral Agents

Identifiers

PMID38467135
PMCPMC11289895

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.