Evidence map›Paper›PMID 38466974›Full record

ArticleJMIR research protocols2024

Identifying and Validating Alcohol Diagnostics for Injury-Related Trauma in South Africa: Protocol for a Mixed Methods Study.

Petal Petersen Williams, Megan Prinsloo, Margaret M Peden, Ian Neethling, Shibe Mhlongo, Sithombo Maqungo, Charles Parry, Richard Matzopoulos

Abstract read
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Article in JMIR research protocols, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Petal Petersen Williams *Mental Health, Alcohol, Substance use and Tobacco Research Unit, South African Medical Research Council, Cape Town, South Africa.ORCID https://orcid.org/0000-0001-5535-2458
Megan Prinsloo *Burden of Disease Research Unit, South African Medical Research Council, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-0415-0973
Margaret M Peden *George Institute for Global Health UK, Imperial College London, London, United Kingdom.ORCID https://orcid.org/0000-0003-0872-9851
Ian NeethlingBurden of Disease Research Unit, South African Medical Research Council, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-2778-4995
Shibe MhlongoGender and Health Research Unit, South African Medical Research Council, Pretoria, South Africa.ORCID https://orcid.org/0000-0003-3093-6646
Sithombo MaqungoOrthopaedic Trauma Service, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-8735-8341
Charles Parry *Mental Health, Alcohol, Substance use and Tobacco Research Unit, South African Medical Research Council, Cape Town, South Africa.ORCID https://orcid.org/0000-0001-9787-2785
Richard Matzopoulos *Burden of Disease Research Unit, South African Medical Research Council, Cape Town, South Africa.ORCID https://orcid.org/0000-0001-9063-6210

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe burden of alcohol use among patients with trauma and the relative injury risks is not routinely measured in South Africa. Given the prominent burden of alcohol on hospital trauma departments, South Africa needs practical, cost-effective, and accurate alcohol diagnostic tools for testing, surveillance, and clinical management of patients with trauma.

objectiveThis study aims to validate alcohol diagnostics for injury-related trauma and assess its use for improving national health practice and policy.

methodsThe Alcohol Diagnostic Validation for Injury-Related Trauma study will use mixed methods across 3 work packages. Five web-based focus group discussions will be conducted with 6 to 8 key stakeholders, each across 4 areas of expertise (clinical, academic, policy, and operational) to determine the type of alcohol information that will be useful for different stakeholders in the injury prevention and health care sectors. We will then conduct a small pilot study followed by a validation study of alcohol diagnostic tools (clinical assessment, breath analysis, and fingerprick blood) against enzyme immunoassay blood concentration analysis in a tertiary hospital trauma setting with 1000 patients. Finally, selected alcohol diagnostic tools will be tested in a district hospital setting with a further 1000 patients alongside community-based participatory research on the use of the selected tools.

resultsPilot data are being collected, and the protocol will be modified based on the results.

conclusionsThrough this project, we hope to identify and validate the most appropriate methods of diagnosing alcohol-related injury and violence in a clinical setting. The findings from this study are likely to be highly relevant and could influence our primary beneficiaries-policy makers and senior health clinicians-to adopt new practices and policies around alcohol testing in injured patients. The findings will be disseminated to relevant national and provincial government departments, policy experts, and clinicians. Additionally, we will engage in media advocacy and with our stakeholders, including community representatives, work through several nonprofit partners to reach civil society organizations and share findings. In addition, we will publish findings in scientific journals. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/52949.

Indexed as

accidentaccidentsaddictionAfricaalcoholalcohol diagnosticsalcohol misuseclinical managementdiagnosticdiagnostic tooldiagnostic toolsinjuriesinjuryinjury preventionmixed methodsriskroad trafficSouth Africasurveillancetraumaviolence

Identifiers

PMID38466974
PMCPMC10964142

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.