ArticleInternational journal of colorectal disease2024
Predictors of recurrence and long-term patient reported outcomes following surgical repair of anal fistula, a retrospective analysis.
Article in International journal of colorectal disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Failure rates and complications of four sphincter-sparing techniques for the treatment of fistula-in-ano: a systematic review and network meta-analysis.Techniques in coloproctology · 2025Pooled it
- Comparative analysis of early and late recurrence rates in perianal fistula surgery.Experimental and therapeutic medicine · 2026Article
- Intraoperative Flexible Rectoscopy for Internal Opening Identification in Transsphincteric Perianal Fistula: A Feasible and Accessible Adjunct to Seton Placement.Medicina (Kaunas, Lithuania) · 2026Article
- Per-endoscopic rectal fistulotomy: A new endoscopic rectal myotomy technique to support the management of complex anorectal fistulas.Endoscopy · 2026Article
- Use of microfragmented autologous adipose tissue (LIPOGEMS®) as a sphincter-saving therapy for complex anal fistulas: a single-center retrospective study.BMC surgery · 2026Observational
- Comparison of incision and drainage procedure with drainage and ligation of the intersphincteric fistula tract in the treatment of deep perianal abscess.Scientific reports · 2026Article
- Intraluminal bioink robotic patch deposition system for complex perianal fistulas in Crohn's disease.Annals of medicine and surgery (2012) · 2026Article
- Risk factors for fecal incontinence after surgery for cryptoglandular anal fistula: Protocol of a meta-analytic study.PloS one · 2026Article
- Development and validation of a SHAP-interpretable GBM model for predicting postoperative recurrence of anal Fistula.Frontiers in surgery · 2026Article
- Impact of diabetes mellitus and glycemic control on postoperative recurrence of perianal abscess: a retrospective, single-center study.Frontiers in medicine · 2026Article
- Pathophysiological mechanisms and clinical management of type 2 diabetes mellitus complicated with anal fistula.Frontiers in surgery · 2026Review
- Chinese traditional medicine complex hemorrhoidal analgesic cream promotes wound healing in diabetic rats after anal fistula surgery via Keap1/Nrf2 signaling pathway.Biochemistry and biophysics reports · 2025Article
- Article
- External validation of the modified Parks classification of cryptoglandular anal fistula to predict failure of healing: the protocol for a retrospective analysis.International journal of surgery protocols · 2025Article
- Mid- and long-term functional outcomes of advancement flap for cryptoglandular perianal fistulas.Techniques in coloproctology · 2025Article
- Mucosal advancement flap versus ligation of the inter-sphincteric fistula tract for management of trans-sphincteric perianal fistulas in the elderly: a retrospective study.International journal of colorectal disease · 2025Observational
- Technical approach in the management of perianal fistula: combining ovine extracellular matrix with endoanal ultrasound to review the surgical outcome.Annals of coloproctology · 2025Article
- Is Primary Opening of Fistula-in-Ano Always at Dentate Line: Correlation Between MRI and Operative Findings in 379 Patients.Clinical and experimental gastroenterology · 2025Article
- Modified anal sphincter suspension improves anal function in patients with anal fistula.American journal of translational research · 2024Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSurgery for anal fistulas can result in devastating complications, including reoperations and fecal incontinence. There is limited contemporary evidence comparing outcomes since the adoption of the ligation of intersphincteric fistula tract procedure into mainstream practice. The purpose of this study is to compare recurrence rates and long-term outcomes of anal fistula following repair.
methodsData was collected from the electronic medical records or patient reported outcomes from patients aged 18 or older with a primary or recurrent cryptoglandular anal fistula. Primary outcome was recurrence defined as the identification of at least one fistula os or a high clinical suspicion of anal fistula. Secondary outcomes included fecal incontinence and postoperative quality of life.
resultsA total of 171 patients underwent definitive surgical repairs for their anal fistula. So 66.5% had a simple fistula, and 33.5% had a complex fistula. Of the 171 patients, 12.5% had a recurrence. The recurrence rates were 5.9% for simple fistula and 25.4% for complex fistula. Predictors of recurrence included diabetes mellitus, history of anorectal abscess, complex fistula, and sphincter sparing surgery. LIFT or plug/biologic procedures were both associated with a 50% or greater recurrence rate. No significant differences were found in fecal incontinence or associated quality of life between sphincter sparing or non-sphincter sparing surgical resections.
conclusionThe study provides insights into the long-term outcomes of surgical repair for anal fistula. We demonstrate that sphincter sparing operations are associated with increased recurrence, meanwhile, non-sphincter sparing surgeries did not increase the risk of fecal incontinence or worsen quality of life.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.