ReviewEuropean archives of psychiatry and clinical neuroscience2025
The neurobiological effects of childhood maltreatment on brain structure, function, and attachment.
Review in European archives of psychiatry and clinical neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Multi-epigenome-wide analyses and meta-analysis of child maltreatment in judicial autopsies and intervened children and adolescents.Molecular psychiatry · 2026Pooled it
- Movement-Anchored Emotional Memory: An Embodied Neuropsychological Framework.Journal of clinical medicine · 2026Review
- The Association Between Childhood Trauma and Meaning in Life: The Mediating Role of Self-Compassion in Iranian Adults.Brain and behavior · 2026Article
- Article
- Mapping Patterns of Parental Burnout Along Psychological Resources and Parenting Styles.Behavioral sciences (Basel, Switzerland) · 2026Article
- Neurodevelopmental impacts of unique postnatal adversity subgroups in children with prenatal alcohol exposure.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2026Article
- Mapping behavioural mechanisms linking childhood maltreatment, cognition, impulsivity, and suicidality in bipolar disorder: A network approach.Translational psychiatry · 2026Article
- The relationship between childhood trauma, doomscrolling, and dating violence among university students in Türkiye.BMC psychology · 2026Article
- Dynamic frontoparietal flexibility and cognitive dysfunction in schizophrenia: disentangling the roles of symptom burden and childhood trauma.Psychological medicine · 2026Article
- Structural and functional atypicality in the temporal cortex are associated with auditory perception in maltreated children.Scientific reports · 2026Article
- Childhood Adversity and Reactive Attachment Disorder in Adolescents: A Systematic Review.Journal of child & adolescent trauma · 2026Article
- Posttraumatic Stress Symptoms and Anger Among Police Officers Following a Fatal Knife Attack on a Team Member.Healthcare (Basel, Switzerland) · 2026Article
- Inter-individual differentially methylated region-targeted EWAS reveals epigenetic signatures of early childhood adversity.Epigenomics · 2026Article
- Review
- Central-peripheral neuroimmune dynamics in psychological stress and depression: insights from current research.Molecular psychiatry · 2025Review
- Risky family environment, white matter organization, and effective parenting in expectant fathers.Development and psychopathology · 2025Article
- The relationship between childhood emotional abuse and maladaptive parenting practices.Child protection and practice · 2025Article
- Adverse childhood experiences and level of self-esteem as predictors for motivation to change among adults with methamphetamine use residing in rehabilitation centers.BMC psychology · 2025Article
- Article
- Mindfulness-based interventions for preventing childhood maltreatment and restoring health among survivors: a public health perspective.Mindfulness · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Childhood maltreatment is a risk factor for psychopathologies, and influences brain development at specific periods, particularly during early childhood and adolescence. This narrative review addresses phenotypic alterations in sensory systems associated with specific types of childhood maltreatment exposure, periods of vulnerability to the neurobiological effects of maltreatment, and the relationships between childhood maltreatment and brain structure, function, connectivity, and network architecture; psychopathology; and resilience. It also addresses neurobiological alterations associated with maternal communication and attachment disturbances, and uses laboratory-based measures during infancy and case-control studies to elucidate neurobiological alterations in reactive attachment disorders in children with maltreatment histories. Moreover, we review studies on the acute effects of oxytocin on reactive attachment disorder and maltreatment and methylation of oxytocin regulatory genes. Epigenetic changes may play a critical role in initiating or producing the atypical structural and functional brain alterations associated with childhood maltreatment. However, these changes could be reversed through psychological and pharmacological interventions, and by anticipating or preventing the emergence of brain alterations and subsequent psychopathological risks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.