ArticleInvestigative ophthalmology & visual science2024
Quantitative Evaluation of the Topographical Maps of Three-Dimensional Choroidal Vascularity Index in Children With Different Degrees of Myopia.
Article in Investigative ophthalmology & visual science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Associations Between Choroidal Structural Parameters and Cone Photoreceptors in Young High Myopia.Translational vision science & technology · 2026Article
- Anatomical and Transcriptional Alterations in the Mouse Choroid Induced by All-Trans Retinoic Acid.Investigative ophthalmology & visual science · 2026Article
- Investigation of 3D choroidal components in myopic populations using ultra-widefield OCTA.Eye (London, England) · 2026Article
- Quantitative evaluation of the topographical maps of three-dimensional choroidal vascularity index in gestational diabetes mellitus: a cross-sectional observational study.BMC pregnancy and childbirth · 2026Observational
- Choroidal structural and perfusion characteristics across refractive groups in children.Frontiers in medicine · 2026Article
- Short-Term Choroidal and Retinal Structural Changes in Myopic Children Treated with 0.05% Atropine.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- The Relationship of Photopic and Mesopic Contrast Sensitivity to Retinal-Choroidal Structural Characteristics in Low-to-Moderate and High Myopia.Translational vision science & technology · 2025Article
- Three-dimensional choroidal parameter differences in myopic anisometropia.BMC ophthalmology · 2025Article
- Elevated Nasal-Temporal Asymmetry of the Choroidal Vascular Index in Pathologically Myopic Eyes.Investigative ophthalmology & visual science · 2025Article
- Choroidal Features of Cynomolgus Macaques in Relation to Age and Axial Length.Investigative ophthalmology & visual science · 2025Article
- Assessment of choriocapillary flow deficits in myopic children by optical coherence tomography angiography.Scientific reports · 2025Article
- Comprehensive Visualization of Choroidal Alterations in Thyroid Eye Disease With Ultra-Widefield OCT Angiography.Investigative ophthalmology & visual science · 2025Article
- Detection of macular and peripheral ocular microvascular changes after carotid artery revascularization using widefield SS-OCTA.Frontiers in medicine · 2025Article
- Effects of orthokeratology lenses on choroidal thickness and choriocapillaris perfusion in myopic children.Frontiers in medicine · 2025Article
- Choroid vascular index in myopic patients - A mini review.Taiwan journal of ophthalmologyReview
- Choroidal Characteristics in 3- to 16-Year-Old Chinese Patients, Measured by Swept-Source OCT/OCT Angiography.Ophthalmology scienceArticle
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11 authors.
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Abstract
Purpose: To investigate topographical maps of the three-dimensional choroidal vascularity index (3D-CVI) in children with different levels of myopia. Methods: We enrolled 274 eyes from 143 children with various severity of myopia, including emmetropia (EM), low myopia (LM), and moderate-high myopia (MHM). The choroidal vessel volume (CVV), choroidal stroma volume (CSV), and 3D-CVI in different eccentricities (fovea, parafovea, and perifovea) and quadrants (nasal, temporal, superior, and inferior) were obtained from swept-source optical coherence tomography angiography (SS-OCTA) volume scans. All choroidal parameters were compared among groups, and the associated factors contributing to different 3D-CVIs were analyzed. Results: Compared to the less myopic group, the more myopic group showed a significant decrease in CVV and CSV (MHM < LM < EM) and a significant increase in the 3D-CVI (MHM > LM > EM) in most areas (all P < 0.05). The nasal quadrant had the greatest 3D-CVI and lowest CSV and CVV, and vice versa in the temporal quadrant. The 3D-CVIs of the EM and LM groups gradually increased from the fovea to the perifovea, whereas the 3D-CVI of the MHM group first decreased and then increased. Regression analysis showed that axial length was an independent risk factor affecting foveal and parafoveal 3D-CVIs. Restricted cubic spline analysis revealed that the 3D-CVI increased with spherical equivalent (SE) when the SE was less than threshold and decreased when the SE was greater than threshold (SE thresholds for foveal, parafoveal, and perifoveal 3D-CVIs were -5.25 D, -5.125 D, and -2.00 D, respectively; all P < 0.05). Conclusions: Children with myopia exhibited decreased CSV and CVV, increased 3D-CVIs, and altered 3D-CVI eccentricity characteristics (from the fovea to the perifovea). The quadratic relationship between the 3D-CVI and SE should be explored in longitudinal investigations.
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