Evidence map›Paper›PMID 38466202›Full record

ArticleInhalation toxicology2024

Biological effects of diesel exhaust inhalation. III cardiovascular function.

Kristine Krajnak, Hong Kan, Janet A Thompson, Walter McKinney, Stacey Waugh, Tim South, Dru Burns, Ryan Lebouf, Jared Cumpston, Theresa Boots and 1 more

Open access · greenAbstract read
In one paragraph

Article in Inhalation toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Kristine KrajnakPhysical Effects Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Hong KanPathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Janet A ThompsonPathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Walter McKinneyPhysical Effects Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Stacey WaughPhysical Effects Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Tim SouthPhysical Effects Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Dru BurnsRespiratory Health Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Ryan LeboufRespiratory Health Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Jared CumpstonAnimal Facilities, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Theresa BootsRisk Evaluation Branch, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Jeffrey S FedanPathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
National Institute for Occupational Safety and Health · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

objectiveInhalation of diesel exhaust (DE) has been shown to be an occupational hazard in the transportation, mining, and gas and oil industries. DE also contributes to air pollution, and therefore, is a health hazard to the general public. Because of its effects on human health, changes have been made to diesel engines to reduce both the amounts of particulate matter and volatile fumes they generate. The goal of the current study was to examine the effects of inhalation of diesel exhaust. MATERIALS AND

methodsThe study presented here specifically examines the effects of exposure to 0.2 and 1.0 mg/m

resultsExposure to 0.2 mg/m DISCUSSION AND

conclusionsBased on the results of this study, we suggest that exposure to DE generated by a Tier 2 compliant diesel engine generates acute effects on biomarkers indicative of cardiovascular dysfunction. Recovery occurs quickly with most measures of vascular/cardiovascular function returning to baseline levels by 7d following exposure.

Indexed as

Air PollutantsAir PollutionAnimalsBiomarkersHumansInhalation ExposureMaleParticulate MatterRatsVehicle EmissionsAir PollutantsBiomarkersParticulate MatterVehicle EmissionsBlood pressurecardiac functiondiesel exhaustparticulatevascular function

Identifiers

PMID38466202
PMCPMC11099779
OpenAlexW4392662297

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.