ArticleJournal of veterinary internal medicine
Effect of institutional antimicrobial stewardship guidelines on prescription of critically important antimicrobials for dogs and cats.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Carriage of antimicrobial-resistant E. coli in urban stray cats (Felis catus).Australian veterinary journal · 2026Article
- Interventions to Reduce Antibiotic Prescribing in Small Animal Veterinary Practice: Evidence and Clinical Impact.Antibiotics (Basel, Switzerland) · 2026Review
- Formulation and In Vitro Evaluation of Red Palm Oil withVeterinary sciences · 2026Article
- Benchmarking: A Tool for Veterinary Practices to Improve Prudent Use of Antibiotics in Cats and Dogs in Switzerland.Antibiotics (Basel, Switzerland) · 2026Article
- Efflux pump overexpression in fluoroquinolone multidrug resistance: molecular mechanisms, PK/PD implications, global epidemiology, and translational strategies.Frontiers in pharmacology · 2026Review
- Antimicrobial Susceptibility of Subgingival Bacteria in Canines With Periodontal Disease.Veterinary medicine international · 2026Article
- Antimicrobial Consumption and Utilisation in Zambia: Results from the Analysis of National Data for the Human and Animal Health Sectors.Antibiotics (Basel, Switzerland) · 2025Article
- Antimicrobial Resistance Profiles of Bacteria Isolated from the Animal Health Sector in Zambia (2020-2024): Opportunities to Strengthen Antimicrobial Resistance Surveillance and Stewardship Programs.Antibiotics (Basel, Switzerland) · 2025Article
- In vitro fermentation characteristics of dietary fibers using fecal inocula from dogs treated with metronidazole.Animal microbiome · 2025Article
- Article
- Antimicrobial Prescribing Practices Among Sri Lankan Veterinarians for Common Medical Conditions in Companion Animals.Animals : an open access journal from MDPI · 2024Article
- Effect of institutional antimicrobial stewardship guidelines on prescription of critically important antimicrobials for dogs and cats.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundVeterinary hospital antimicrobial stewardship (AMS) guidelines might help combat antimicrobial resistance (AMR).
objectivesDetermine the conditions and types of infection for which antimicrobial drugs (AMDs) deemed critically important (CIA) by the World Health Organization (WHO) were prescribed and assess the effect of hospital AMS guidelines on adherence to International Society for Companion Animal Infectious Diseases published guidelines for the treatment of superficial bacterial folliculitis, respiratory tract disease and urinary tract infection in these cases. ANIMALS: Dogs and cats managed at an academic veterinary hospital from 1/21 to 6/21 and 9/21 to 6/22.
methodsPrescriptions of cephalosporins (third or fourth generation), glycopeptides, macrolides/ketolides, polymyxins, and quinolones were identified. Data on culture and susceptibility (C/S) testing and previous AMD exposure were collected. Frequencies were compared between time periods using Fisher's exact test with Bonferroni corrections.
resultsIn animals prescribed ≥1 WHO-CIA AMD, fluoroquinolones were the most frequently prescribed WHO-CIA class in dogs (567/1724, 32.9%) and cats (192/450, 42.7%). No animals were prescribed carbapenems, dihydrofolate reductase inhibitors/sulfonamides, or polymyxins. No cats were prescribed aminoglycosides or amphenicols. Institutional guidelines were followed in 57.8% (324/561) cases. The most frequent causes of nonadherence were failure to perform C/S testing 46.0% (109/237) and unnecessary use of a higher-tier AMD 43.0% (102/237). Bacterial C/S testing was more frequently performed after AMS guideline institution (59.7% vs. 46.8%, P = 0.0006). CONCLUSIONS AND CLINICAL IMPORTANCE: Adherence to published guidelines remained poor despite an increase in C/S testing. There were no changes in the frequencies of confirmed infections, positive cultures or AMD resistance between time periods.
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