Evidence map›Paper›PMID 38465828›Full record

ArticleTherapeutic advances in respiratory disease

All-cause and cause-specific mortality by spirometric pattern and sex - a population-based cohort study.

Helena Backman, Sami Sawalha, Ulf Nilsson, Linnea Hedman, Caroline Stridsman, Lowie E G W Vanfleteren, Bright I Nwaru, Nikolai Stenfors, Eva Rönmark, Anne Lindberg

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. [Development of a machine learning-based model for assessing pulmonary function in elderly patients].Nan fang yi ke da xue xue bao = Journal of Southern Medical University
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Helena BackmanSection of Sustainable Health/The OLIN Unit, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Sami SawalhaDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.ORCID 0000-0003-0473-9227
Ulf NilssonDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Linnea HedmanSection of Sustainable Health/The OLIN Unit, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Caroline StridsmanDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.ORCID 0000-0001-6622-3838
Lowie E G W VanfleterenCOPD Center, Sahlgrenska University Hospital, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Bright I NwaruKrefting Research Center, Institution of Medicine, University of Gothenburg, Gothenburg, Sweden.
Nikolai StenforsDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Eva RönmarkSection of Sustainable Health/The OLIN Unit, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Anne LindbergDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.ORCID 0000-0002-3292-7471
Umeå University · SESahlgrenska University Hospital · SEUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic airway obstruction (CAO) and restrictive spirometry pattern (RSP) are associated with mortality, but sex-specific patterns of all-cause and specific causes of death have hardly been evaluated.

objectivesTo study the possible sex-dependent differences of all-cause mortality and patterns of cause-specific mortality among men and women with CAO and RSP, respectively, to that of normal lung function (NLF).

designPopulation-based prospective cohort study.

methodsIndividuals with CAO [FEV

resultsThe adjusted hazard for all-cause mortality was higher in CAO and RSP than in NLF (HR, 95% CI; 1.69, 1.31-2.02 and 1.24, 1.06-1.71), and the higher hazards were driven by males. CAO had a higher hazard of respiratory and cardiovascular death than NLF (2.68, 1.05-6.82 and 1.40, 1.04-1.90). The hazard of respiratory death was significant in women (3.41, 1.05-11.07) while the hazard of cardiovascular death was significant in men (1.49, 1.01-2.22). In RSP, the higher hazard for respiratory death remained after adjustment (2.68, 1.05-6.82) but not for cardiovascular death (1.11, 0.74-1.66), with a similar pattern in both sexes.

conclusionThe higher hazard for all-cause mortality in CAO and RSP than in NLF was male driven. CAO was associated with respiratory death in women and cardiovascular death in men, while RSP is associated with respiratory death, similarly in both sexes.

Indexed as

Pulmonary Disease, Chronic ObstructiveCause of DeathCohort StudiesFemaleForced Expiratory VolumeHumansLungMaleProspective StudiesSpirometryVital Capacitycause of deathchronic airway obstructionepidemiologymortalityrestrictive spirometric pattern

Identifiers

PMID38465828
PMCPMC10929033
OpenAlexW4392666163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.