ArticleThe annals of applied statistics2020
EVIDENCE FACTORS IN A CASE-CONTROL STUDY WITH APPLICATION TO THE EFFECT OF FLEXIBLE SIGMOIDOSCOPY SCREENING ON COLORECTAL CANCER.
Article in The annals of applied statistics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed, 3 citations in OpenAlex.
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3 authors at 3 institutions in 1 country.
Funding
Abstract
As in any observational study, in a case-control study a primary concern is potential unmeasured confounders. Bias, due to unmeasured confounders, can result in a false discovery of an apparent treatment effect when there is none. Replication of an observational study, which tries to provide multiple analyses of the data where the biases affecting each analysis are thought to be different, is one way to strengthen the evidence from an observational study. Evidence factors allow for internal replication by testing a hypothesis using multiple comparisons in a way that the comparisons yield independent evidence and differ in the sources of potential bias. We construct evidence factors in a case-control study in which there are two types of cases, "narrow" cases which are thought to be potentially more affected by the exposure and "marginal" cases which are thought to have more heterogeneous causes. We develop and study an inference procedure for using such evidence factors and apply it to a study of the effect of sigmoidoscopy screening on colorectal cancer.
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