Evidence map›Paper›PMID 38465198›Full record

ArticleClinical and translational discovery2023

Translational implications of targeting annexin A2: From membrane repair to muscular dystrophy, cardiovascular disease and cancer.

Victor G Kayejo, Hannah Fellner, Roshan Thapa, Peter A Keyel

Abstract read
In one paragraph

Article in Clinical and translational discovery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Victor G KayejoDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409.
Hannah FellnerDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409.
Roshan ThapaDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409.
Peter A KeyelDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409.

Funding

Novel membrane defense systems utilized by the human pathogen LeishmaniaR21AI156225 · NIAID · TEXAS TECH UNIVERSITY · PI KEYEL, PETER A · 2021 to 2022
$405k
NIAID NIH HHS R21 AI156225
6 · The paper itself

Abstract

Annexin A2 (A2) contributes to several key cellular functions and processes, including membrane repair. Effective repair prevents cell death and degeneration, especially in skeletal or cardiac muscle, epithelia, and endothelial cells. To maintain cell integrity after damage, mammalian cells activate multiple membrane repair mechanisms. One protein family that facilitates membrane repair processes are the Ca

Indexed as

annexincancercardiovascular diseasemembrane repairmuscular dystrophy

Identifiers

PMID38465198
PMCPMC10923526

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.