Evidence map›Paper›PMID 38465016›Full record

Observational studyThe Pan African medical journal2023

Factors related to serum levels of intercellular adhesion molecule-1 in probable COVID-19 patients in surgical treatment: an observational study.

Mendy Hatibie Oley, Maximillian Christian Oley, Fima Lanra Fredrik Gerald Langi, Billy Johnson Kepel, Jacob Pajan, Regina Elizabeth Meriam Kepel, Angelica Maurene Joicetine Wagiu, Ferry Kalitouw, Laurens Kalesaran, Muhammad Faruk

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in The Pan African medical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mendy Hatibie OleyDivision of Plastic Reconstructive and Aesthetic Surgery, Department of Surgery, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Maximillian Christian OleyDivision of Neurosurgery, Department of Surgery, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Fima Lanra Fredrik Gerald LangiDepartment Epidemiology and Biostatistics, Public Health Faculty, Sam Ratulangi University, Manado, Indonesia.
Billy Johnson KepelDepartment of Chemistry, Faculty of Medicine, Sam Ratulangi University, Manado, North Sulawesi, Indonesia.
Jacob PajanDepartment of Surgery, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Regina Elizabeth Meriam KepelNorth Sulawesi Regional Hospital, Manado, Indonesia.
Angelica Maurene Joicetine WagiuDepartment of Surgery, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Ferry KalitouwDepartment of Surgery, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Laurens KalesaranDepartment of Surgery, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Muhammad FarukDepartment of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: COVID-19 causes a systemic inflammatory response, involving dysregulation and misexpression of many inflammatory cytokines. The recruitment and activation of inflammatory cells depend on the expression of many classes of inflammatory mediators, with increased expression of endothelial cell adhesion molecules being related to COVID-19 disease severity. With the World Health Organization having recently updated case definitions to suspect, probable, and confirmed, this study aimed to measure the mean value of intercellular adhesion molecule 1 (ICAM-1) and its relation to suspected COVID-19. Methods: all suspected patients (n=20) were hospitalized and treated following the Indonesian National Guidelines for COVID-19 management. ICAM-1 levels were measured on days 1 and 7, demographic data were recorded, and routine blood count values were measured and additionally considered. Results: the results showed that the levels of ICAM-1 in the 1 Conclusion: the mean value of ICAM-1 levels for patients with confirmed positive COVID-19 cases was higher than those with suspected COVID-19 cases.

Indexed as

COVID-19Intercellular Adhesion Molecule-1HumansIntercellular Adhesion Molecule-1COVID-19Intercellular Adhesion Molecule 1patientssurgery

Identifiers

PMID38465016
PMCPMC10924607

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.