Evidence map›Paper›PMID 38465002›Full record

ArticleVeterinarni medicina2024

The effects of Pycnogenol, a pine bark extract on pulmonary inflammation by Asian sand dust in mice.

So-Won Pak, Se-Jin Lee, Woong-Il Kim, Yea-Gin Yang, Young-Kwon Cho, Joong-Sun Kim, Tae-Won Kim, Je-Won Ko, Jong-Choon Kim, Sung-Hwan Kim and 1 more

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Article in Veterinarni medicina, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

So-Won PakCollege of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Buk-gu, Gwangju, Republic of Korea.
Se-Jin LeeCollege of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Buk-gu, Gwangju, Republic of Korea.
Woong-Il KimCollege of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Buk-gu, Gwangju, Republic of Korea.
Yea-Gin YangCollege of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Buk-gu, Gwangju, Republic of Korea.
Young-Kwon ChoCollege of Health Sciences, Cheongju University, Cheongju-si, Chungbuk, Republic of Korea.
Joong-Sun KimCollege of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Buk-gu, Gwangju, Republic of Korea.
Tae-Won KimBK21 FOUR Program, College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea.
Je-Won KoBK21 FOUR Program, College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea.
Jong-Choon KimCollege of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Buk-gu, Gwangju, Republic of Korea.
Sung-Hwan KimJeonbuk Branch, Korea Institute of Toxicology (KIT), Jeongeup-si, Jeonbuk, Republic of Korea.
In-Sik ShinCollege of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Buk-gu, Gwangju, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asian sand dust (ASD), also called China dust or yellow dust, mainly occurs in East Asia during spring and autumn. Because ASD enters the body mainly through the respiratory system, it can cause respiratory disorders or worsen underlying diseases. Because of this, it has become an important health concern that threatens the well-being of humans and animals. In this study, we investigated the effects of 15 and 30 mg/kg of Pycnogenol (PYC15 and 30 groups), a pine bark extract, on ASD-induced pulmonary inflammation in mice. We evaluated the inflammatory cell counts, inflammatory cytokines, and matrix-metalloproteinase (MMP)-9 expression in animal models. PYC administration significantly decreased inflammatory cell infiltration into lung tissue; this was accompanied by a reduction in the levels of proinflammatory mediators including interleukin (IL)-1β (

Indexed as

airway inflammationfine dustMMP-9Pinus pinaster Aiton

Identifiers

PMID38465002
PMCPMC10919100

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.