ArticleWorld journal of clinical cases2024
Assessment of the triglyceride glucose index in adult patients with chronic diarrhea and constipation.
Article in World journal of clinical cases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Deciphering the Association Between Homeostatic Model Assessment of Insulin Resistance and Chronic Diarrhea and the Mediating Role of Lymphocyte-to-Monocyte Ratio.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026Article
- Association between the Zhejiang University index and chronic diarrhea: a cross-sectional study.European journal of medical research · 2025Article
- CTI as a biomarker for diarrhea in U.S. adults: insights from NHANES 2005-2010.BMC gastroenterology · 2025Article
- Predictive value of the triglyceride-glucose index for coronary artery bypass grafting-acute kidney injury patients.BMC cardiovascular disorders · 2025Article
- Evaluating the role of insulin resistance in chronic intestinal health issues: NHANES study findings.Frontiers in nutrition · 2025Article
- Independent role of two novel abdominal fat indicators in chronic diarrhoea.Frontiers in medicine · 2025Article
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Authors and funding
3 authors.
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Abstract
backgroundAccumulating evidence suggests that the gut microbiome is involved in the pathogenesis of insulin resistance (IR). However, the link between two of the most prevalent bowel disorders, chronic diarrhea and constipation, and the triglyceride glucose (TyG) index, a marker of IR, has not yet been investigated.
aimTo investigate the potential association between TyG and the incidence of chronic diarrhea and constipation.
methodsThis cross-sectional study enrolled 2400 participants from the National Health and Nutrition Examination Survey database from 2009-2010. TyG was used as an exposure variable, with chronic diarrhea and constipation as determined by the Bristol Stool Form Scale used as the outcome variables. A demographic investigation based on TyG quartile subgroups was performed. The application of multivariate logistic regression models and weighted generalized additive models revealed potential correlations between TyG, chronic diarrhea, and constipation. Subgroup analyses were performed to examine the stability of any potential associations.
resultsIn the chosen sample, chronic diarrhea had a prevalence of 8.00%, while chronic constipation had a prevalence of 8.04%. In multiple logistic regression, a more prominent positive association was found between TyG and chronic diarrhea, particularly in model 1 (OR = 1.45; 95%CI: 1.17-1.79,
conclusionHigher TyG levels were positively associated with abnormal bowel health.
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