ReviewInternational journal of rheumatology2024
Primary Immune Thrombocytopenic Purpura (ITP) and ITP Associated with Systemic Lupus Erythematosus: A Review of Clinical Characteristics and Treatment Modalities.
Review in International journal of rheumatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Perioperative management of a patient with comorbid immune thrombocytopenia and antiphospholipid syndrome undergoing minimally invasive mitral valve surgery.Journal of cardiothoracic surgery · 2026Article
- [Clinical and immunological features for early differentiation between primary immune thrombocytopenia and connective tissue disease in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Article
- Isolated thrombocytopenia as the initial manifestation of childhood-onset systemic lupus erythematosus: A case report.Medicine · 2025Article
- Role of intravenous immunoglobulins in the management of systemic lupus erythematosus: a single-centre experience.Lupus science & medicine · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
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Abstract
Immune thrombocytopenic purpura (ITP) is an immune-mediated disorder characterized by the destruction of platelets and megakaryocytes due to autoantibodies against the platelet surface proteins. ITP without any apparent cause of thrombocytopenia is defined as primary ITP, and ITP in the setting of SLE is secondary ITP, which can be diagnosed after excluding other causes of thrombocytopenia by history, physical examination, and laboratory testing. Patients with ITP associated with SLE have higher median platelet count and less bleeding manifestations compared to the patients with primary ITP. It can be very challenging to diagnose primary ITP in SLE patients as other causes of thrombocytopenia including drug-induced thrombocytopenia, antiphospholipid syndrome, and thrombotic microangiopathic process should be ruled out. Corticosteroids are the main modality of treatment. IVIG can be used in severe cases. Splenectomy was found to be less effective in ITP associated with SLE compared to primary ITP. Control of disease activity with immunosuppressive therapy can be helpful in some cases associated with active disease flares in SLE patients.
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Registered trials
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