Evidence map›Paper›PMID 38464301›Full record

ArticlebioRxiv : the preprint server for biology2024

Mimicking an

Jeffrey W Beard, Samuel L Hunt, Alexander Evans, Coleman Goenner, Benjamin L Miller

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jeffrey W BeardDepartment of Dermatology, University of Rochester, Rochester, NY 14627, USA.ORCID 0000-0001-5294-1708
Samuel L HuntDepartment of Dermatology, University of Rochester, Rochester, NY 14627, USA.
Alexander EvansDepartment of Biomedical Engineering, University of Rochester, Rochester, NY 14627, USA.
Coleman GoennerDepartment of Biochemistry and Biophysics, University of Rochester, Rochester, NY 14627, USA.
Benjamin L MillerDepartment of Dermatology, University of Rochester, Rochester, NY 14627, USA.ORCID 0000-0001-9168-8047

Funding

Paper-based HIV self testR61AI167035 · NIAID · UNIVERSITY OF ROCHESTER · PI MILLER, BENJAMIN L · 2022 to 2024
$1.4M
NIAID NIH HHS R61 AI167035
6 · The paper itself

Abstract

Point of care (PoC) nucleic acid amplification tests (NAATs) are a cornerstone of public health, providing the earliest and most accurate diagnostic method for many communicable diseases, such as HIV, in the same location the patient receives treatment. Communicable diseases disproportionately impact low-resource communities where NAATs are often unobtainable due to the resource intensive enzymes that drive the tests. Enzyme-free nucleic acid detection methods, such as hybridization chain reaction (HCR), use DNA secondary structures for self-driven amplification schemes producing large DNA nanostructures and capable of single molecule detection

Indexed as

diagnosticDNA nanostructuresenzyme-free amplificationhybridization chain reactionmolecular crowdingNucleic acid amplificationsessile droplets

Identifiers

PMID38464301
PMCPMC10925243

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.