Evidence map›Paper›PMID 38464232›Full record

ArticlebioRxiv : the preprint server for biology2024

Heterologous Prime-Boost with Immunologically Orthogonal Protein Nanoparticles for Peptide Immunofocusing.

Sonia Bhattacharya, Matthew C Jenkins, Parisa Keshavarz-Joud, Alisyn Retos Bourque, Keiyana White, Amina M Alvarez Barkane, Anton V Bryksin, Carolina Hernandez, Mykhailo Kopylov, M G Finn

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sonia BhattacharyaSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Matthew C JenkinsSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Parisa Keshavarz-JoudSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Alisyn Retos BourqueParker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Keiyana WhiteSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Amina M Alvarez BarkaneParker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Anton V BryksinParker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Carolina HernandezNew York Structural Biology Center, New York, New York, 10027, USA.
Mykhailo KopylovNew York Structural Biology Center, New York, New York, 10027, USA.
M G FinnSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA.ORCID 0000-0001-8247-3108
Georgia Institute of Technology · USNew York Structural Biology Center · US

Funding

Virus-Like Particle Based Immunization Against Peanut AllergyR21AI166639 · NIAID · GEORGIA INSTITUTE OF TECHNOLOGY · PI FINN, M.G. · 2021 to 2022
$450k
NIAID NIH HHS R21 AI166639
6 · The paper itself

Abstract

Protein nanoparticles are effective platforms for antigen presentation and targeting effector immune cells in vaccine development. Encapsulins are a class of protein-based microbial nanocompartments that self-assemble into icosahedral structures with external diameters ranging from 24 to 42 nm. Encapsulins from

Identifiers

PMID38464232
PMCPMC10925081
OpenAlexW4392189904

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.