Evidence map›Paper›PMID 38464051›Full record

ArticlebioRxiv : the preprint server for biology2024

Evolution of pH-sensitive transcription termination during adaptation to repeated long-term starvation.

Sarah B Worthan, Robert D P McCarthy, Mildred Delaleau, Ryan Stikeleather, Benjamin P Bratton, Marc Boudvillain, Megan G Behringer

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sarah B WorthanDepartment of Biological Sciences, Vanderbilt University, Nashville, TN.ORCID 0000-0001-6581-7159
Robert D P McCarthyDepartment of Biological Sciences, Vanderbilt University, Nashville, TN.
Mildred DelaleauCentre de Biophysique Moléculaire, CNRS UPR4301, affiliated with Université d'Orléans, rue Charles Sadron, 45071 Orléans cedex 2, France.ORCID 0000-0003-1551-3928
Ryan StikeleatherBiodesign Center for Mechanisms of Evolution, Arizona State University, Tempe, AZ.
Benjamin P BrattonEvolutionary Studies Initiative, Vanderbilt University, Nashville, TN.ORCID 0000-0003-1128-2560
Marc BoudvillainCentre de Biophysique Moléculaire, CNRS UPR4301, affiliated with Université d'Orléans, rue Charles Sadron, 45071 Orléans cedex 2, France.ORCID 0000-0002-6398-9122
Megan G BehringerDepartment of Biological Sciences, Vanderbilt University, Nashville, TN.ORCID 0000-0001-7036-6014
Vanderbilt University · USUniversité d'Orléans · FRArizona State University · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALVIN C POWERS · 2012 to 2026
$29.3M
Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6M
Vanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9M
Using Experimental Evolution to Evaluate Environmental Effects on Microbial Mutation and AdaptationR35GM150625 · NIGMS · VANDERBILT UNIVERSITY · PI Megan Grace Behringer · 2023 to 2026
$1.8M
Multi-Excitation TIRF Microscope for Shared ResourceS10OD018075 · OD · VANDERBILT UNIVERSITY · PI WELLS, K. SAM · 2015 to 2015
$370k
NCI NIH HHS P30 CA068485NEI NIH HHS P30 EY008126NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK058404NIDDK NIH HHS U24 DK059637NIGMS NIH HHS R35 GM150625NIH HHS S10 OD018075
6 · The paper itself

Abstract

Fluctuating environments that consist of regular cycles of co-occurring stress are a common challenge faced by cellular populations. For a population to thrive in constantly changing conditions, an ability to coordinate a rapid cellular response is essential. Here, we identify a mutation conferring an arginine-to-histidine (Arg to His) substitution in the transcription terminator Rho. The

Indexed as

adaptationalkaline stresschanging environmentgene regulationphenotypic plasticity

Identifiers

PMID38464051
PMCPMC10925284
OpenAlexW4392351724

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.