Evidence map›Paper›PMID 38464031›Full record

ArticlebioRxiv : the preprint server for biology2024

Discovering and exploring the hidden diversity of human gut viruses using highly enriched virome samples.

Moreno Zolfo, Andrea Silverj, Aitor Blanco-Míguez, Paolo Manghi, Omar Rota-Stabelli, Vitor Heidrich, Jordan Jensen, Sagun Maharjan, Eric Franzosa, Cristina Menni and 9 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Moreno ZolfoDepartment CIBIO, University of Trento, Italy.ORCID 0000-0001-6661-4046
Andrea SilverjDepartment CIBIO, University of Trento, Italy.ORCID 0000-0002-5452-1042
Aitor Blanco-MíguezDepartment CIBIO, University of Trento, Italy.ORCID 0000-0001-7386-5572
Paolo ManghiDepartment CIBIO, University of Trento, Italy.ORCID 0000-0003-0846-6529
Omar Rota-StabelliDepartment CIBIO, University of Trento, Italy.ORCID 0000-0002-0030-7788
Vitor HeidrichDepartment CIBIO, University of Trento, Italy.ORCID 0000-0001-6617-9187
Jordan JensenHarvard Chan Microbiome in Public Health Center, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Sagun MaharjanHarvard Chan Microbiome in Public Health Center, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0001-8369-2804
Eric FranzosaHarvard Chan Microbiome in Public Health Center, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-8798-7068
Cristina MenniDepartment of Twin Research & Genetic Epidemiology, King's College London, London, UK.ORCID 0000-0001-9790-0571
Alessia ViscontiCenter for Biostatistics, Epidemiology and Public Health, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.ORCID 0000-0003-4144-2019
Federica PintoDepartment CIBIO, University of Trento, Italy.ORCID 0000-0002-4539-4811
Matteo CicianiDepartment CIBIO, University of Trento, Italy.ORCID 0000-0003-2045-5435
Curtis HuttenhowerHarvard Chan Microbiome in Public Health Center, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-1110-0096
Anna CeresetoDepartment CIBIO, University of Trento, Italy.ORCID 0000-0003-4453-2597
Francesco AsnicarDepartment CIBIO, University of Trento, Italy.ORCID 0000-0003-3732-1468
Hiroaki KitanoIntegrated Open Systems Unit, Okinawa Institute of Science and Technology (OIST), Okinawa, Japan.ORCID 0000-0002-3589-1953
Takuji YamadaIntegrated Open Systems Unit, Okinawa Institute of Science and Technology (OIST), Okinawa, Japan.
Nicola SegataDepartment CIBIO, University of Trento, Italy.ORCID 0000-0002-1583-5794

Funding

Exploiting Public Metagenomic Data to Uncover Cancer-Microbiome RelationshipsR01CA230551 · NCI · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · PI Levi Waldron · 2020 to 2026
$3.9M
Exploiting public metagenomic data to uncover cancer-microbiome relationshipsU01CA230551 · NCI · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · PI WALDRON, LEVI · 2019 to 2019
$464k
NCI NIH HHS R01 CA230551NCI NIH HHS U01 CA230551
6 · The paper itself

Abstract

Viruses are an abundant and crucial component of the human microbiome, but accurately discovering them via metagenomics is still challenging. Currently, the available viral reference genomes poorly represent the diversity in microbiome samples, and expanding such a set of viral references is difficult. As a result, many viruses are still undetectable through metagenomics even when considering the power of

Identifiers

PMID38464031
PMCPMC10925137

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.