Evidence map›Paper›PMID 38463999›Full record

ArticlebioRxiv : the preprint server for biology2025

CD44 facilitates adhesive interactions in airineme-mediated intercellular signaling.

Raquel L Bowman, Jiyea Kim, Michael J Parsons, Dae Seok Eom

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Raquel L BowmanDepartment of Developmental and Cell Biology, University of California, Irvine, CA 92617, USA.
Jiyea KimDepartment of Developmental and Cell Biology, University of California, Irvine, CA 92617, USA.
Michael J ParsonsDepartment of Developmental and Cell Biology, University of California, Irvine, CA 92617, USA.
Dae Seok EomDepartment of Developmental and Cell Biology, University of California, Irvine, CA 92617, USA.ORCID 0000-0002-0617-8788
University of California, Irvine · US

Funding

DROSOPHILA GENOMICS RESOURCE CENTERP40OD010949 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Andrew Zelhof · 2012 to 2026
$9.4M
Signaling at a distance mediated by vesicles on novel cellular protrusionsR35GM142791 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI EOM, DAE SEOK · 2021 to 2025
$1.9M
NIGMS NIH HHS R35 GM142791NIH HHS P40 OD010949
6 · The paper itself

Abstract

Specialized cellular protrusions facilitate local intercellular communications in various species, including mammals. Among these, airinemes play a crucial role in pigment pattern formation in zebrafish by mediating long-distance Notch signaling between pigment cells. Remarkably, airinemes exhibit large vesicle-like structure at their tips, which are pulled by macrophages and delivered to target cells. The interaction between macrophages and Delta-ligand carrying airineme vesicles is essential for initiating airineme-mediated signaling, yet the molecular detail of this interaction remains elusive. Through high-resolution live imaging, genetic

Identifiers

PMID38463999
PMCPMC10925269
OpenAlexW4392229237

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.