Evidence map›Paper›PMID 38463953›Full record

ArticleResearch square2024

Functional partitioning of sentence processing and emotional prosody in the right perisylvian cortex after perinatal stroke.

Kelly C Martin, Anna Seydell-Greenwald, Peter E Turkeltaub, Catherine E Chambers, William D Gaillard, Elissa L Newport

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In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Kelly C MartinGeorgetown University Medical Center, Georgetown University.
Anna Seydell-GreenwaldGeorgetown University Medical Center, Georgetown University.
Peter E TurkeltaubGeorgetown University Medical Center, Georgetown University.
Catherine E ChambersGeorgetown University Medical Center, Georgetown University.
William D GaillardGeorgetown University Medical Center, Georgetown University.
Elissa L NewportGeorgetown University Medical Center, Georgetown University.

Funding

Neurobehavioral Evaluation CoreP50HD105328 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI LAUREN KENWORTHY · 2021 to 2026
$9.3M
Training in Neural Injury &PlasticityT32NS041218 · NINDS · GEORGETOWN UNIVERSITY · PI MARK P BURNS, Kathleen Anne Maguire-Zeiss · 2001 to 2026
$3.5M
Language and cognition after perinatal strokeR01DC016902 · NIDCD · GEORGETOWN UNIVERSITY · PI GAILLARD, WILLIAM DAVIS, NEWPORT, ELISSA L · 2019 to 2023
$3.0M
Language development and linguistic processing after left hemisphere perinatal strokeK18DC014558 · NIDCD · GEORGETOWN UNIVERSITY · PI NEWPORT, ELISSA L · 2015 to 2016
$349k
NICHD NIH HHS P50 HD105328NIDCD NIH HHS K18 DC014558NIDCD NIH HHS R01 DC016902NINDS NIH HHS T32 NS041218
6 · The paper itself

Abstract

In healthy adults different language abilities-sentence processing versus emotional prosody-are supported by the left (LH) versus the right hemisphere (RH), respectively. However, after LH stroke in infancy, RH regions support both abilities with normal outcomes. We investigated how these abilities co-exist in RH regions after LH perinatal stroke by evaluating the overlap in the activation between two fMRI tasks that probed auditory sentence processing and emotional prosody processing. We compared the overlap for these two functions in the RH of individuals with perinatal stroke with the symmetry of these functions in the LH and RH of their healthy siblings. We found less activation overlap in the RH of individuals with LH perinatal stroke than would be expected if both functions retained their typical spatial layout, suggesting that their spatial segregation may be an important feature of a functioning language system.

Identifiers

PMID38463953
PMCPMC10925448

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.