ArticleHeliyon2024
Development, physicochemical characterization, and antimicrobial evaluation of niosome-loaded oregano essential oil against fish-borne pathogens.
Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed.
- Antibacterial activity of crocin-loaded niosomes against foodborne pathogens isolated from cream pastries.BMC microbiology · 2026Article
- Essential Oils for Biofilm Control: Mechanisms, Synergies, and Translational Challenges in the Era of Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2025Review
- Natural drug delivery systems for the treatment of neurodegenerative diseases.Molecular biology reports · 2025Review
- Antibacterial activities of oregano essential oils and their active components.Frontiers in pharmacology · 2025Article
- Article
- Phytochemicals, promising strategies combatingFrontiers in pharmacology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Niosomes have gained attention as a promising drug delivery system for enhancing the antimicrobial and anti-biofilm effects of natural compounds. Oregano essential oil has demonstrated potent antimicrobial and anti-biofilm properties against food-borne pathogens. Methods: In this study, researchers aimed to explore the use of niosomes as a delivery system to improve the efficacy of oregano essential oil against food-borne pathogens. The structural and morphological properties of different niosome formulations were examined. Different formulations of niosomes were prepared and their structural and morphological properties were examined. The antimicrobial and anti-biofilm effects of niosomes containing oregano essential oil were evaluated using microbroth-dilution and microtiter-plate methods, respectively. The biocompatibility of the synthesized niosomes was assessed using the MTT method on human foreskin fibroblasts normal cell line (HFF). Results: The optimal formulation of niosomes had an average size of 219 nm and an encapsulation efficiency of 61.22%. The release study demonstrated that 58% of the essential oil was released from niosomes, while 100% was released from free essential oil. Furthermore, the antimicrobial and anti-biofilm effects of the essential oil were found to be 2-4 times higher when loaded in niosomes. The biocompatibility test confirmed that the synthesized empty niosomes had no cytotoxic effects on HFF cell line. Conclusion: Niosomes encapsulating oregano essential oil demonstrated the capacity to inhibit the activity of genes associated with biofilm formation in pathogenic bacteria. This study highlights the significant antimicrobial and anti-biofilm effects of niosomes containing oregano essential oil, suggesting their potential as a suitable drug delivery system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.