Evidence map›Paper›PMID 38463680›Full record

ArticleJACC. Asia2024

Differential Impact of Fractional Flow Reserve Measured After Coronary Stent Implantation by Left Ventricular Dysfunction.

Ki Hong Choi, Woochan Kwon, Doosup Shin, Seung-Hun Lee, Doyeon Hwang, Jinlong Zhang, Chang-Wook Nam, Eun-Seok Shin, Joon-Hyung Doh, Shao-Liang Chen and 24 more

Registry-linked trialAbstract read
In one paragraph

Article in JACC. Asia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04684043 (Prognostic Implications of Physiologic Investigation After Revascularization With Stent), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04684043 unknown statusnot on this map

Prognostic Implications of Physiologic Investigation After Revascularization With Stent

TypeobservationalSponsorBon-Kwon KooRan2020 to 2021Enrolled5,100ConditionsCoronary DiseaseArmsPercutaneous coronary intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Ki Hong ChoiDivision of Cardiology, Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Woochan KwonDivision of Cardiology, Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Doosup ShinDivision of Cardiology, Department of Internal Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Seung-Hun LeeDivision of Cardiology, Department of Internal Medicine, Heart Center, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea.
Doyeon HwangDepartment of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea.
Jinlong ZhangDepartment of Cardiology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Chang-Wook NamDepartment of Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea.
Eun-Seok ShinDepartment of Cardiology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
Joon-Hyung DohDepartment of Medicine, Inje University Ilsan-Paik Hospital, Goyang, Korea.
Shao-Liang ChenDivision of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Tsunekazu KakutaDivision of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Ibaraki, Japan.
Gabor G TothUniversity Heart Centre Graz, Medical University Graz, Austria.
Zsolt PirothGottsegen National Cardiovascular Centre, Budapest, Hungary.
Abdul HakeemDivision of Cardiovascular Diseases and Hypertension, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, New Jersey, USA.
Barry F UretskyCentral Arkansas VA Health System/University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Yohei HokamaDepartment of Cardiology, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.
Nobuhiro TanakaDepartment of Cardiology, Ajou University School of Medicine, Suwon, Korea.
Hong-Seok LimDepartment of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Tsuyoshi ItoDepartment of Cardiology, Kyoto Second Red Cross Hospital, Kyoto, Japan.
Akiko MatsuoDivision of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, USA.
Lorenzo AzzaliniDivision of Cardiovascular Diseases, University of Alabama, Birmingham, Alabama, USA.
Massoud A LeesarDepartment of Interventional Cardiology, Thoraxcenter, Erasmus University Medical Centre, Rotterdam, the Netherlands.
Joost DaemenWest of Scotland Regional Heart and Lung Centre, Golden Jubilee National Hospital, Glasgow, United Kingdom.
Damien CollisonCardiovascular Center Aalst, Aalst, Belgium.
Carlos ColletDepartment of Cardiology, University of Lausanne, Switzerland.
Bernard De BruyneDepartment of Cardiology, University of Lausanne, Switzerland.
Bon-Kwon KooDepartment of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea.
Taek Kyu ParkDivision of Cardiology, Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Jeong Hoon YangDivision of Cardiology, Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Young Bin SongDivision of Cardiology, Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Joo-Yong HahnDivision of Cardiology, Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Seung-Hyuk ChoiDivision of Cardiology, Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Hyeon-Cheol GwonDivision of Cardiology, Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Joo Myung LeeDivision of Cardiology, Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Both left ventricular systolic function and fractional flow reserve (FFR) are prognostic factors after percutaneous coronary intervention (PCI). However, how these prognostic factors are inter-related in risk stratification of patients after PCI remains unclarified. Objectives: This study evaluated differential prognostic implication of post-PCI FFR according to left ventricular ejection fraction (LVEF). Methods: A total of 2,965 patients with available LVEF were selected from the POST-PCI FLOW (Prognostic Implications of Physiologic Investigation After Revascularization with Stent) international registry of patients with post-PCI FFR measurement. The primary outcome was a composite of cardiac death or target-vessel myocardial infarction (TVMI) at 2 years. The secondary outcome was target-vessel revascularization (TVR) and target vessel failure, which was a composite of cardiac death, TVMI, or TVR. Results: Post-PCI FFR was independently associated with the risk of target vessel failure (per 0.01 decrease: HR Conclusions: Post-PCI FFR had differential prognostic impact according to LVEF. Residual ischemia by post-PCI FFR ≤0.80 was a prognostic indicator for cardiac death or TVMI among patients with patients with LVEF ≤40%, and it was associated with TVR among patients with patients with LVEF>40%. (Prognostic Implications of Physiologic Investigation After Revascularization with Stent [POST-PCI FLOW]; NCT04684043).

Indexed as

drug-eluting stent(s)fractional flow reserveleft ventricular ejection fractionpercutaneous coronary interventionprognosis

Identifiers

PMID38463680
PMCPMC10920040

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.