Evidence map›Paper›PMID 38463595›Full record

ArticleAmerican journal of translational research2024

Predictive value of coagulation function, alpha-fetoprotein and placental growth factor in patients with perilous placenta previa.

Yuan Qiao, Jin Xiao, Tongqiang He, Rui Wang, Yehong Xu, Yang Wei, Jun Wang, Rui Hu, Zhibin Li

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Article in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Yuan QiaoObstetrics and Gynecology Intensive Care Unit, Northwest Women's and Children's Hospital No. 1616 Yanxiang Road, Xi'an 710061, Shaanxi, China.
Jin XiaoObstetrics and Gynecology Intensive Care Unit, Northwest Women's and Children's Hospital No. 1616 Yanxiang Road, Xi'an 710061, Shaanxi, China.
Tongqiang HeObstetrics and Gynecology Intensive Care Unit, Northwest Women's and Children's Hospital No. 1616 Yanxiang Road, Xi'an 710061, Shaanxi, China.
Rui WangDepartment of Obstetrics, Northwest Women's and Children's Hospital No. 1616 Yanxiang Road, Xi'an 710061, Shaanxi, China.
Yehong XuDepartment of Obstetrics, Northwest Women's and Children's Hospital No. 1616 Yanxiang Road, Xi'an 710061, Shaanxi, China.
Yang WeiObstetrics and Gynecology Intensive Care Unit, Northwest Women's and Children's Hospital No. 1616 Yanxiang Road, Xi'an 710061, Shaanxi, China.
Jun WangObstetrics and Gynecology Intensive Care Unit, Northwest Women's and Children's Hospital No. 1616 Yanxiang Road, Xi'an 710061, Shaanxi, China.
Rui HuObstetrics and Gynecology Intensive Care Unit, Northwest Women's and Children's Hospital No. 1616 Yanxiang Road, Xi'an 710061, Shaanxi, China.
Zhibin LiDepartment of Obstetrics, Northwest Women's and Children's Hospital No. 1616 Yanxiang Road, Xi'an 710061, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the predictive value of coagulation function, alpha-fetoprotein (AFP) and placental growth factor (PIGF) for postpartum hemorrhage in patients with perilous placenta previa (PPP).

methodsThe clinical data of 104 PPP patients were retrospectively analyzed. The patients were divided into a hemorrhage group (n=68) and a non-hemorrhage group (n=36). A total of 55 healthy pregnant women were recruited as controls. The coagulation function, AFP and PIGF were compared between the three groups. Multivariate logistic regression was performed to determine independent risk factors for hemorrhage.

resultsPT, TT, APTT, FIB and AFP were significantly higher while PIGF was lower in the PPP group than the control group (all P<0.05). Placental adhesion (OR 3.924, 95% CI 1.389-11.083, P=0.01), anterior placenta (OR 4.583, 95% CI 1.589-13.22, P=0.005), AFP (OR 0.208, 95% CI 0.068-0.635, P=0.006) and PIGF (OR 3.963, 95% CI 1.385-11.34, P=0.01) were independent risk factors for hemorrhage.

conclusionCoagulation function, AFP and PIGF could predict postpartum hemorrhage in PPP patients.

Indexed as

alpha-fetoproteinCoagulation functionmassive hemorrhageperilous placenta previaplacental growth factorprediction

Identifiers

PMID38463595
PMCPMC10918133

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.