New-onset tachycardia-bradycardia syndrome following acute non-medullary brainstem infarction.

Jingmin Zhao, Yu Gao, Zhengxian Jin, Yujing Huang, Kwee-Yum Lee, Guangxun Shen

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Article in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Jingmin ZhaoDepartment of Neurology, China-Japan Union Hospital of Jilin University Changchun, Jilin, China.

Yu GaoDepartment of Neurology, China-Japan Union Hospital of Jilin University Changchun, Jilin, China.

Zhengxian JinDepartment of Neurology, China-Japan Union Hospital of Jilin University Changchun, Jilin, China.

Yujing HuangDepartment of Neurology, China-Japan Union Hospital of Jilin University Changchun, Jilin, China.

Kwee-Yum LeeDepartment of Orthopaedic Surgery and Musculoskeletal Medicine, University of Otago Dunedin, New Zealand.

Guangxun ShenDepartment of Neurology, China-Japan Union Hospital of Jilin University Changchun, Jilin, China.

Funding

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6 · The paper itself

Abstract

Tachycardia-bradycardia syndrome (TBS) is a variant of sick sinus syndrome (SSS) characterized by alternating tachycardia and bradycardia. A few cases of SSS secondary to structural lesions in the medulla have been reported, but there has never been a reported case of the rare sign akin to TBS following acute non-medullary brainstem infarction. Furthermore, new-onset cardiac arrhythmias in stroke often presented in one continuous pattern - either as bradycardia or tachycardia, but instances of an alternating fashion have been rarely reported. We present the case of a 46-year-old female who developed severe dizziness with vomiting, diplopia, and slurred speech, which gradually worsened to quadriplegia, severe hypophonia, and dysphagia. Brain magnetic resonance imaging (MRI) demonstrated acute midbrain and pontine infarction. Except for neurological symptoms, the patient experienced unexpected TBS with the symptoms of excessive sweating, palpitations, and irritability without any other predisposing factors. The frequency of the episodes gradually declined until it spontaneously disappeared the 5

Indexed as

central autonomic networkintracranial pressurenon-medullary brainstem infarctionTachycardia-bradycardia syndrome

Identifiers

PMID38463582

PMCPMC10918127

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