ArticleJournal of conservative dentistry and endodontics2024
Effect of collagen cross-linking agents on the depth of penetration of bioceramic sealer and release of hydroxyproline: An
Article in Journal of conservative dentistry and endodontics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed.
- The recovery effect of dentin biomodifiers on microtensile bond strength and sealer-penetration depth of coronal and radicular dentin: an in vitro experimental study.Restorative dentistry & endodontics · 2026Article
- Impact of collagen cross-linking agents on release of hydroxyproline from radicular dentin in endodontically treated mandibular premolars with bio-ceramic sealers: AnJournal of conservative dentistry and endodontics · 2025Article
- Article
- Evolution of Dental Resin Adhesives-A Comprehensive Review.Journal of functional biomaterials · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Context: During endodontic treatment, sealers seal off dentinal tubules and prevent microbial attack. Bioceramic sealers have excellent bioactivity, but its high alkalinity is found to have detrimental effects on radicular collagen. Collagen cross linkers have the ability to chemically modify collagen and can prevent the detrimental effects of the sealer. Aim: This research was aimed to assess the effect of collagen cross-linking agents on the integrity of radicular collagen matrix and depth of penetration of sealer. Materials and Methods: Mandibular premolars ( Statistical Analysis: Wilcoxon signed-rank test and Kruskal-Wallis test for release of HYP and paired Results: Significantly lower release of HYP was seen in proanthocyanin-treated group. Sealer penetration was better for both the proanthocyanin- and CHX-treated groups when compared to saline. Conclusion: Surface treatment with collagen cross-linkers caused a decrease in the amount of HYP released, indicating lesser degradation of collagen. Sealer penetration was better due to the removal of smear layer following the surface treatments.
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Registered trials
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