Evidence map›Paper›PMID 38463419›Full record

ArticleNeurotrauma reports2024

Investigating the Association Between Extended Participation in Collision Sports and Fluid Biomarkers Among Masters Athletes.

Lauren P Giesler, William T O'Brien, Georgia F Symons, Sabrina Salberg, Gershon Spitz, Robb Wesselingh, Terence J O'Brien, Richelle Mychasiuk, Sandy R Shultz, Stuart J McDonald

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In one paragraph

Article in Neurotrauma reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lauren P GieslerDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
William T O'BrienDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Georgia F SymonsDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Sabrina SalbergDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Gershon SpitzDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Robb WesselinghDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Terence J O'BrienDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Richelle MychasiukDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Sandy R ShultzDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Stuart J McDonaldDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traumatic brain injuries (TBIs) and concussions are prevalent in collision sports, and there is evidence that levels of exposure to such sports may increase the risk of neurological abnormalities. Elevated levels of fluid-based biomarkers have been observed after concussions or among athletes with a history of participating in collision sports, and certain biomarkers exhibit sensitivity toward neurodegeneration. This study investigated a cohort of 28 male amateur athletes competing in "Masters" competitions for persons >35 years of age. The primary objective of this study was to compare the levels of blood and saliva biomarkers associated with brain injury, inflammation, aging, and neurodegeneration between athletes with an extensive history of collision sport participation (i.e., median = 27 years; interquartile range = 18-44, minimum = 8) and those with no history. Plasma proteins associated with neural damage and neurodegeneration were measured using Simoa

Indexed as

concussionGFAPinflammationneurodegenerationNfLp-tau-181tautelomereUCH-L1

Identifiers

PMID38463419
PMCPMC10923547

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.