Evidence map›Paper›PMID 38463240›Full record

ArticleNature synthesis2023

Accessing three-dimensional molecular diversity through benzylic C-H cross-coupling.

Si-Jie Chen, Cyndi Qixin He, May Kong, Jun Wang, Shishi Lin, Shane W Krska, Shannon S Stahl

Open access · greenAbstract read
In one paragraph

Article in Nature synthesis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Direct Benzylic C-H Etherification Enabled by Base-Promoted Halogen Transfer.Angewandte Chemie (International ed. in English) · 2024
    Article
  5. Article
  6. A General Three-Component Alkyl Petasis Boron-Mannich Reaction.Journal of the American Chemical Society · 2024
    Article
  7. Article
  8. Article
  9. Polar Heterobenzylic C(spJournal of the American Chemical Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Si-Jie ChenDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI, USA.
Cyndi Qixin HeDepartment of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ, USA.
May KongDepartment of Discovery Chemistry, Merck & Co., Inc., South San Francisco, CA, USA.
Jun WangDepartment of Discovery Chemistry, Merck & Co., Inc., South San Francisco, CA, USA.
Shishi LinDepartment of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ, USA.
Shane W KrskaDepartment of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ, USA.
Shannon S StahlDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI, USA.
Merck & Co., Inc., Rahway, NJ, USA (United States) · USUniversity of Wisconsin–Madison · US

Funding

Catalytic Redox Reactions for Pharmaceutical SynthesisR35GM134929 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Shannon S Stahl · 2020 to 2026
$4.3M
QExactive (Orbitrap) mass spectrometerS10OD020022 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI VESTLING, MARTHA M · 2015 to 2015
$483k
NIGMS NIH HHS R35 GM134929NIH HHS S10 OD020022
6 · The paper itself

Abstract

Pharmaceutical and agrochemical discovery efforts rely on robust methods for chemical synthesis that rapidly access diverse molecules

Identifiers

PMID38463240
PMCPMC10923599
OpenAlexW4379016551

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.