Evidence map›Paper›PMID 38463121›Full record

ReviewAnnals of medicine and surgery (2012)2024

Immediate impacts of COVID-19 vaccination on glycemic control in type 1 diabetes mellitus: a systematic review and meta-analysis.

Pratik Lamichhane, Hussain Khalid, Cijoy Kanatte Siviyachan, Summiya Zafar, Mahesh Prasanth, Kapil Khanal, Anushka Agrawal, Loveleen Kaur Jhajj

Abstract readReview
In one paragraph

Review in Annals of medicine and surgery (2012), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pratik LamichhaneMaharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal.
Hussain KhalidDepartment of Internal Medicine, Darlington Memorial Hospital, UK.
Cijoy Kanatte SiviyachanHoly cross super specialty hospital, Kollam, Kerala, India.
Summiya ZafarJinnah Sindh Medical University, Karachi, Pakistan.
Mahesh PrasanthMedical University of Gdansk, Gdańsk, Poland.
Kapil KhanalMaharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal.
Anushka AgrawalMaharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal.
Loveleen Kaur JhajjXavier University School of Medicine, Oranjestad, Aruba.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: COVID-19 vaccination is recommended in diabetic patients since diabetes is associated with worse clinical outcomes in COVID-19 infection. The safety profile of different types of COVID-19 vaccines, especially on glycemic control, can be explored due to availability of data from continuous glucose monitoring (CGM) devices. This meta-analysis aimed to quantify the impact of COVID-19 vaccination on glycemic control in patients with type 1 diabetes mellitus (T1DM). Methods: A systematic search of PubMed, Embase, and Google Scholar was conducted using a search strategy for studies published till January 2023 in English language. Comparative observational studies reporting glycemic control obtained from CGM before and after COVID-19 vaccination in T1DM patients were included. The primary outcome was time in range (TIR) metric of proportion of glucose results falling within the range: 3.9-10 mmol/l. Other outcomes were time above range (TAR) (>10 mmol/l), time below range (TBR) (<3.9 mmol/l), coefficient of variation (CV), and mean blood glucose levels. The pooled outcomes were compared pre-vaccination and post-vaccination using Hedges' g (HG) with 95% CI. Results: A total of seven studies (632 participants) were included in the meta-analysis. COVID-19 vaccination caused small and statistically insignificant decrease in TIR after both the first (HG = 0.21, 95% CI: -0.02 to 0.44, Conclusion: COVID-19 vaccination has an excellent safety profile in T1DM patients owing to its minimal impacts on immediate glycemic control.

Indexed as

adverse drug reactionscontinuous glucose monitoringCOVID-19time in rangevaccination

Identifiers

PMID38463121
PMCPMC10923380

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.