Evidence map›Paper›PMID 38462231›Full record

ArticleJornal de pediatria

Alert for the high prevalence of vitamin D deficiency in adolescents in a large Brazilian sample.

Vanessa Radonsky, Marise Lazaretti-Castro, Maria Izabel Chiamolera, Rosa Paula Mello Biscolla, José Viana Lima Junior, José Gilberto Henriques Vieira, Cynthia Maria Alvares Brandão, Rodrigo Fernandes Ramalho, Sergio Setsuo Maeda, Marcia Wehba Esteves Cavichio

Open access · goldAbstract read
In one paragraph

Article in Jornal de pediatria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Sleep Duration and Sun Exposure in Portuguese Children: Associations With Obesity Indicators.American journal of human biology : the official journal of the Human Biology Council · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Vanessa RadonskyUniversidade Federal de São Paulo (UNIFESP), Departamento Endocrinologia, São Paulo, SP, Brazil.
Marise Lazaretti-CastroUniversidade Federal de São Paulo (UNIFESP), Departamento Endocrinologia, São Paulo, SP, Brazil. Electronic address: marise.lazaretti@imabrasil.com.br.
Maria Izabel ChiamoleraUniversidade Federal de São Paulo (UNIFESP), Departamento Endocrinologia, São Paulo, SP, Brazil; Grupo Fleury, Departamento Endocrinologia, São Paulo, SP, Brazil.
Rosa Paula Mello BiscollaUniversidade Federal de São Paulo (UNIFESP), Departamento Endocrinologia, São Paulo, SP, Brazil; Grupo Fleury, Departamento Endocrinologia, São Paulo, SP, Brazil.
José Viana Lima JuniorUniversidade Federal de São Paulo (UNIFESP), Departamento Endocrinologia, São Paulo, SP, Brazil; Grupo Fleury, Departamento Endocrinologia, São Paulo, SP, Brazil.
José Gilberto Henriques VieiraUniversidade Federal de São Paulo (UNIFESP), Departamento Endocrinologia, São Paulo, SP, Brazil; Grupo Fleury, Departamento Endocrinologia, São Paulo, SP, Brazil.
Cynthia Maria Alvares BrandãoGrupo Fleury, Departamento Endocrinologia, São Paulo, SP, Brazil.
Rodrigo Fernandes RamalhoGrupo Fleury, Grupo de Ciências de Dados e Bioinformática, São Paulo, SP, Brazil.
Sergio Setsuo MaedaUniversidade Federal de São Paulo (UNIFESP), Departamento Endocrinologia, São Paulo, SP, Brazil.
Marcia Wehba Esteves CavichioGrupo Fleury, Departamento Pediatria, São Paulo, SP, Brazil.
Fleury S.A. (Brazil) · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo estimate the prevalence of vitamin D deficiency and severe deficiency in children and adolescents, in a large Brazilian sample. METHODOLOGY: Results of 413,988 25(OH)D measurements in children and adolescents aged 0 to 18 years collected between 01/2014 and 10/2018 were obtained from the database of a Clinical Laboratory. In this population, 25 hydroxyvitamin D concentrations below 20 ng/mL are considered deficient, and below 12 ng/mL as severe deficiency. All measurements were performed by immunoassay and the results were distributed by gender, age group, seasonality, and latitude.

resultsThe mean of 25(OH)D levels was 29.2 ng/mL with a standard deviation of 9.2 ng/mL. Of the total samples, 0.8% had a concentration < 12 ng/mL, and 12.5% of the samples had a concentration < 20 ng/mL, with a higher prevalence in females. Children under 2 years of age had the lowest prevalence. The effects of latitude and seasonality were quite evident. In samples of female adolescents from the southern region in winter, 36% of vitamin D deficiency and 5% of severe deficiency were found.

conclusionIn this large number of measurements of 25(OH)D in children and adolescents, 12.5% had a deficiency and 0.8% had severe deficiency. A greater deficiency was observed among adolescents, especially females, which raises questions about the need for supplementation during this period of life.

Indexed as

SeasonsVitamin DVitamin D DeficiencyAdolescentAge DistributionBrazilChildChild, PreschoolFemaleHumansInfantInfant, NewbornMalePrevalenceSex Distribution25-hydroxyvitamin DVitamin D25 Hydroxyvitamin DAdolescentChildhoodCholecalciferolRicketsVitamin D

Identifiers

PMID38462231
PMCPMC11331242
OpenAlexW4392542779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.